Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of the study is to quantitatively characterize the flow in the pelvic venous structures using 2D and 4D flow MRI with the objective of establishing physiologic and pathologic parameters for downstream computational fluid dynamics analysis. Arm 1: To establish the baseline flow characteristics of the iliac veins in patients with no imaging evidence of iliac venous disease. Arm 2: To assess the flow characteristics of the iliac veins in patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome). Arm 3: To assess the flow characteristics of the iliac veins in patients status post iliac stent placement.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: t
View:

• • No self-reported history of pelvic or iliac venous disease or associated symptoms

• • Clinical symptoms or imaging findings compatible with left iliac vein compression syndrome

• • History of left iliac vein stent placement

Locations
United States
Massachusetts
University of Massachusetts
RECRUITING
Worcester
Contact Information
Primary
Noelle Bodkin
noelle.bodkin@umassmed.edu
774-441-8442.
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2027-01-01
Participants
Target number of participants: 15
Treatments
Experimental: Patients with no imaging evidence of iliac venous disease
Healthy volunteers with no self-reported history or prior imaging evidence of pelvic venous disease or associated symptoms to undergo 2D and 4D flow MRI without contrast administration
Experimental: Patients with left iliac vein compression syndrome (a.k.a. May-Thurner syndrome).
Patients with prior imaging evidence of left common iliac vein compression syndrome to undergo 2D and 4D flow MRI without contrast administration
Experimental: Patients status post iliac stent placement
Patients with a history of iliac stent placement to undergo 2D and 4D flow MRI without contrast administration
Related Therapeutic Areas
Sponsors
Leads: Ningcheng Peter Li

This content was sourced from clinicaltrials.gov