Characterization of the Melanoma-Specific Immune Response
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The aim of this study is to study T-cells. Blood will be collected and the samples will be used to generate T cell clones. Two separate blood draws will be required at the maximum.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: t
View:
• Biopsy diagnosis of malignant melanoma
• Have had a biopsy diagnosis of malignant melanoma in the past
Locations
United States
California
University of California, Davis Department of Dermatology
RECRUITING
Sacramento
Contact Information
Primary
Emanual Maverakis, M.D.
emaverakis@ucdavis.edu
916-734-1267
Backup
Lauren Downing
ladowning@ucdavis.edu
916-551-2635
Time Frame
Start Date: 2007-08
Estimated Completion Date: 2024-08
Participants
Target number of participants: 20
Treatments
1
Subjects ages 18-85 years old with biopsy proven melanoma. Peripheral blood will be collected from adults ages 18-85 years old. These samples will then be used for PCR analysis and to generate melanoma-specific T cell clones. If the participant requires a palliative resection of a melanoma tumor(s) then tissue from the tumor will be used to characterize the melanoma's interaction with the immune system and to generate melanoma-specific cell lines. T cell clones isolated from participant's peripheral blood will then be assayed for in-vitro responsiveness to these cell lines. All experiments will be conducted in-vitro.
2
Age-matched controls (no evidence of melanoma)
Related Therapeutic Areas
Sponsors
Leads: University of California, Davis