Oral Metformin in the Treatment of Melasma: a Prospective Trial in Latin American Women

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

The goal of this clinical trial is to learn if metformin can treat melasma in Latin American women. The main question it aims to answer is: \- Can metformin help reduce the dark patches of melasma? Researchers will test two different doses of metformin (500 mg and 1000 mg) to see if either one helps improve melasma. Participants will: * Take a metformin pill every day for three months. * Go to the clinic twice: once at the beginning and once at the end of the study. * Get a phone call from the researchers to check how they're doing and ask about any changes or side effects.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 21
Healthy Volunteers: f
Locations
Other Locations
Puerto Rico
Administración de Servicios Médicos (ASEM) Clinicas Externas
RECRUITING
San Juan
Contact Information
Primary
Cristina Brau
cbrau@skinbybrau.com
787-758-2525
Backup
Camila Cordero
camila.cordero@upr.edu
Time Frame
Start Date: 2025-02-20
Estimated Completion Date: 2025-05-30
Participants
Target number of participants: 30
Treatments
Experimental: Metformin
Participants received oral metformin tablets, starting at 500 mg once daily. At week 4, those who tolerated the medication increased to 500 mg twice daily for the remainder of the study.
Related Therapeutic Areas
Sponsors
Leads: University of Puerto Rico

This content was sourced from clinicaltrials.gov