Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy (C3G) or Primary Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN): A Multi-Country Study
Status: Recruiting
Location: See all (99) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The purpose of this study is to evaluate the effectiveness and safety of Pegcetacoplan in patients with C3G and primary IC-MPGN in the real-world setting. This study will also assess biomarkers not routinely measured in clinical practice. Results will support the long-term evaluation of the benefit-risk profile of pegcetacoplan in a broad patient population, informing clinical decision-making.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Have received or plan to receive pegcetacoplan for the treatment of C3G or primary IC-MPGN.
• Provided signed and dated informed consent. For participants under the legal age signed and dated informed consent is provided by the participant's legally authorised representative. Assent will also be obtained from paediatric participants as required by local regulations.
Locations
Other Locations
Australia
Nepean Hospital
NOT_YET_RECRUITING
Kingswood
Princess Alexandra Hospital
NOT_YET_RECRUITING
Woolloongabba
Austria
Medizinische Universität Graz
NOT_YET_RECRUITING
Graz
Uniklinik Innsbruck
NOT_YET_RECRUITING
Innsbruck
Allgemeines Krankenhaus Wien Universitätsklinik
NOT_YET_RECRUITING
Vienna
Klinik Ottakring
NOT_YET_RECRUITING
Vienna
Belgium
Cliniques Universitaires Saint-Luc
NOT_YET_RECRUITING
Brussels
University hosptial of Antwerpen
NOT_YET_RECRUITING
Edegem
Grand Hôpital de Charleroi
NOT_YET_RECRUITING
Gilly
UZ Leuven
NOT_YET_RECRUITING
Leuven
Centre Hospitalier Universitaire de Liege
NOT_YET_RECRUITING
Liège
CHU UCL Namur
NOT_YET_RECRUITING
Namur
Canada
University of Calgary - Alberta Children's Hospital
NOT_YET_RECRUITING
Calgary
Kingston General Hospital
NOT_YET_RECRUITING
Kingston
London Health Sciences Centre (LHSC) - Victoria Hospital
NOT_YET_RECRUITING
London
CHU Sainte-Justine
NOT_YET_RECRUITING
Montreal
McGill University
NOT_YET_RECRUITING
Montreal
The Hospital for Sick Children
NOT_YET_RECRUITING
Toronto
University Health Network
NOT_YET_RECRUITING
Toronto
British Columbia Childrens' & Women's Hospital Center
NOT_YET_RECRUITING
Vancouver
France
CHU Bordeaux
NOT_YET_RECRUITING
Bordeaux
CHU Lyon - Hôpital Femme-Mère-Enfant
NOT_YET_RECRUITING
Bron
Hopital Henri Mondor
NOT_YET_RECRUITING
Créteil
Hopital Claude Huriez - CHU Lille
NOT_YET_RECRUITING
Lille
Hopital de la Conception - APHM
NOT_YET_RECRUITING
Marseille
Hopital Lapeyronie pt
NOT_YET_RECRUITING
Montpellier
CHU Nantes - Hôtel Dieu
NOT_YET_RECRUITING
Nantes
AP-HP Georges-Pompidou European Hospital (Paris)
NOT_YET_RECRUITING
Paris
Hôpital Necker - Enfants Malades
NOT_YET_RECRUITING
Paris
Hôpital Robert Debré - Paris
NOT_YET_RECRUITING
Paris
Hôpital Saint-Louis
NOT_YET_RECRUITING
Paris
Tenon CHU Paris Est
NOT_YET_RECRUITING
Paris
CHU Reims - Hôpital Maison Blanche
NOT_YET_RECRUITING
Reims
CHU Strasbourg - Nouvel Hôpital Civil
NOT_YET_RECRUITING
Strasbourg
Hôpital Foch
NOT_YET_RECRUITING
Suresnes
Germany
Universitaetsklinikum Aachen AOeR
NOT_YET_RECRUITING
Aachen
Charité - Campus Virchow-Klinikum
NOT_YET_RECRUITING
Berlin
University Hospital Cologne
NOT_YET_RECRUITING
Cologne
Universitaetsklinikum Carl Gustav Carus TU Dresden
NOT_YET_RECRUITING
Dresden
Universitaetsklinikum Erlangen
NOT_YET_RECRUITING
Erlangen
Universitaetsklinikum Essen
NOT_YET_RECRUITING
Essen
Universitaetsklinikum Essen
NOT_YET_RECRUITING
Essen
Universitaetsklinikum Hamburg-Eppendorf
NOT_YET_RECRUITING
Hamburg
Medizinische Hochschule Hannover
NOT_YET_RECRUITING
Hanover
Universitaetsklinikum Heidelberg
NOT_YET_RECRUITING
Heidelberg
Universitaetsklinikum Leipzig AoeR
NOT_YET_RECRUITING
Leipzig
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz
NOT_YET_RECRUITING
Mainz
Universitaetsklinikum Regensburg
NOT_YET_RECRUITING
Regensburg
Robert-Bosch-Krankenhaus
NOT_YET_RECRUITING
Stuttgart
Nephrologisches Zentrum Villingen-Schwenningen
NOT_YET_RECRUITING
Villingen-schwenningen
Nierenzentrum Wiesbaden
NOT_YET_RECRUITING
Wiesbaden
Italy
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
NOT_YET_RECRUITING
Bari
Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS
NOT_YET_RECRUITING
Bologna
Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi
NOT_YET_RECRUITING
Bologna
Ospedali Riuniti di Foggia
NOT_YET_RECRUITING
Foggia
Azienda Ospedaliera Universitaria Gaetano Martino
NOT_YET_RECRUITING
Messina
Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico
NOT_YET_RECRUITING
Milan
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
NOT_YET_RECRUITING
Roma
Ospedale Pediatrico Bambino Gesù
NOT_YET_RECRUITING
Roma
Azienda Ospedaliero-Universitaria Santa Maria della Misericordia
NOT_YET_RECRUITING
Udine
Republic of Korea
Keimyung University Dongsan Hospital
NOT_YET_RECRUITING
Daegu
Chungnam National University Hospital
NOT_YET_RECRUITING
Daejeon
Seoul National University Bundang Hospital
NOT_YET_RECRUITING
Seongnam
Samsung Medical Center
NOT_YET_RECRUITING
Seoul
Seoul Metropolitan Government Seoul National University Boramae Medical Center
NOT_YET_RECRUITING
Seoul
Seoul National University Hospital
NOT_YET_RECRUITING
Seoul
Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITING
Seoul
The Catholic University of Korea, Seoul St. Mary's Hospital
NOT_YET_RECRUITING
Seoul
Saudi Arabia
King Faisal Specialist Hospital & Research Center
NOT_YET_RECRUITING
Jeddah
King Fahad Medical City
NOT_YET_RECRUITING
Riyadh
King Faisal Specialist Hospital & Research Center
NOT_YET_RECRUITING
Riyadh
Spain
Complejo Hospitalario Universitario A Coruña
RECRUITING
A Coruña
Hospital Clinic de Barcelona
NOT_YET_RECRUITING
Barcelona
Hospital Sant Joan de Deu
NOT_YET_RECRUITING
Barcelona
Hospital Universitari Vall d'Hebron - VHIR
NOT_YET_RECRUITING
Barcelona
Hospital Universitario de la Palma
NOT_YET_RECRUITING
Las Palmas
Hospital General Universitario Gregorio Marañon
NOT_YET_RECRUITING
Madrid
Hospital La Paz
NOT_YET_RECRUITING
Madrid
Hospital Universitario 12 de Octubre
NOT_YET_RECRUITING
Madrid
Hospital Regional Universitario de Malaga
NOT_YET_RECRUITING
Málaga
Hospital Doctor Peset Valencia
NOT_YET_RECRUITING
Valencia
Hospital Universitari i Politecnic La Fe
NOT_YET_RECRUITING
Valencia
Switzerland
University of Basel
NOT_YET_RECRUITING
Basel
Inselspital - University Hospital Bern
NOT_YET_RECRUITING
Bern
Hôpitaux Universitaires de Genève - HUG
NOT_YET_RECRUITING
Geneva
CHUV, Lausanne University Hospital
NOT_YET_RECRUITING
Lausanne
University Hospital Zurich
NOT_YET_RECRUITING
Zurich
University Hospital Zurich - Children's Hospital Zurich
NOT_YET_RECRUITING
Zurich
Taiwan
Taipei Veterans General Hospital
NOT_YET_RECRUITING
Taipei
United Kingdom
Cambridge University Hospitals NHS Foundation Trust
NOT_YET_RECRUITING
Cambridge
University Hospital of Wales
NOT_YET_RECRUITING
Cardiff
Royal Hospital for Children
NOT_YET_RECRUITING
Glasgow
Leicester General Hospital
NOT_YET_RECRUITING
Leicester
Evelina London Children's Hospital
NOT_YET_RECRUITING
London
Imperial College Healthcare NHS Trust (ICH)
NOT_YET_RECRUITING
London
Royal Free Hospital
NOT_YET_RECRUITING
London
Royal Manchester Children's Hospital
NOT_YET_RECRUITING
Manchester
Newcastle Hospital NHS Foundation Trust
NOT_YET_RECRUITING
Newcastle
Salford Care Organisation
NOT_YET_RECRUITING
Salford
Contact Information
Primary
Study Physician
medical.info@sobi.com
+46 86972000
Time Frame
Start Date: 2026-07-09
Estimated Completion Date: 2032-01-31
Participants
Target number of participants: 150
Treatments
Other: Single arm
Related Therapeutic Areas
Sponsors
Collaborators: IQVIA Pty Ltd
Leads: Swedish Orphan Biovitrum