Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of the Combination of Levilactobacillus Brevis KABP-052, Lactiplantibacillus Plantarum KABP-051 and Pediococcus Acidilactici KABP-021 on Menopausal Symptoms and Quality of Life in Peri- and Post-menopausal Women
In this study, we want to investigate if the active product consisting of a probiotic blend can potentiate the recirculation of active oestrogens into the bloodstream and help to mitigate menopause symptoms, which are closely related to oestrogens levels
• Perimenopausal or post-menopausal women with spontaneous menopause and amenorrhoea for less than 2 years
• Self reported menopausal symptoms (5 or more hot flashes/night sweats per day or 35 or more per week recorded daily for 14 consecutive days)
• BMI between 18.5 and 34.9 kg/m2
• Menopause rating score II (MRS-II) total score of 9 or more at baseline visit
• Willing to sign Informed Consent Form
• Willing to not make relevant changes to their current dietary or lifestyle habits during study
• Able to follow study procedures
• If perimenopausal, agrees to use an accepted method of contraception for duration of study.