A Pilot Study to Evaluate Equol and Its Effects on Menopausal Symptoms Experienced by Women in Singapore

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The main aim of this study is to evaluate the effect of equol on menopausal symptoms of women. Our hypothesis is that equol producers will have milder menopausal symptoms compared to non-equol producers. Equol is known as a metabolite produced by gut microbiota from soy-related diet and has estrogen-like activity compared to the isoflavones from soybean. Previous studies have shown that some women can produce equol from soy-related diet, but the others cannot because they don't have the bacteria which can metabolite daidzein in gut even if they take isoflavones thorough soybean products. This study will involve participants consuming a soy protein bar and collection of urine samples before and after its consumption.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 60
Healthy Volunteers: t
View:

• \- Women aged 40-60

Locations
Other Locations
Singapore
KK Women's and Children's Hospital
RECRUITING
Singapore
Contact Information
Primary
Seng Bin Dr Ang
ang.seng.bin@singhealth.com.sg
+65 6394 1102
Time Frame
Start Date: 2025-07-02
Estimated Completion Date: 2025-12
Participants
Target number of participants: 300
Related Therapeutic Areas
Sponsors
Collaborators: Otsuka Pharmaceutical Co., Ltd.
Leads: Ang Seng Bin

This content was sourced from clinicaltrials.gov