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Effects of 12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep and Psychological Wellbeing - a Randomised, Placebo-controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Perimenopause is a transition phase into menopause, characterised by menopausal symptoms while menstrual periods are still occurring. Common symptoms of perimenopause include hot flushes, night sweats, mood swings, anxiety, sleep disturbances, fatigue, and cognitive difficulties. These symptoms can be both frequent and intense, with the potential to significantly deteriorate women's quality of life. Despite an increase in public discourse around menopause, there are still large gaps in knowledge. Previous literature has suggested a relationship between diet and menopause management. However, studies in this area are limited and women often rely on social media for advice on supplements to address menopause complaints. One supplement that has received a lot of attention with purported benefits for menopause is magnesium, primarily due to its links to energy and or/sleep, however no studies have explored psychological effects of magnesium supplementation in perimenopause. The aim of this study is to explore the effects of 12-weeks magnesium supplementation on perimenopause symptoms, cognition, sleep, and psychological well-being.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 60
Healthy Volunteers: t
View:

• Self-assess as healthy

• Report experiencing troublesome peri-menopause symptoms in the past 6 months but not post-menopausal (defined as 12 months with no periods)

Locations
Other Locations
United Kingdom
School of Psychology, Northumbria University
RECRUITING
Newcastle Upon Tyne
Contact Information
Primary
Crystal Haskell-Ramsay
crystal.haskell-ramsay@northumbria.ac.uk
+44 191 2274875
Time Frame
Start Date: 2025-12-09
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 58
Treatments
Placebo_comparator: Placebo
Placebo capsule consumed for 84 days
Experimental: 375mg magnesium hydroxide
Magnesium hydroxide capsule consumed for 84 days
Related Therapeutic Areas
Sponsors
Leads: Northumbria University
Collaborators: Vitabiotics

This content was sourced from clinicaltrials.gov