Menopause Clinical Trials

Find Menopause Clinical Trials Near You

AGEWISE: Unravelling the Gut-Hormone Axis in Women's Ageing

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

AGEWISE is an observational study that aims to understand how changes in gut microbiome are related to hormonal changes during women's ageing, particularly across the different stages of menopause. The study will include healthy women aged 40 to 64 years living in Portugal, who will provide stool and blood samples and complete questionnaires about their health, lifestyle, diet, and menopausal symptoms. Researchers will study the gut microbiome together with hormone levels and markers of inflammation to better understand how menopause affects long-term health and to support the development of improved prevention strategies for women.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 64
Healthy Volunteers: f
View:

• Female sex

• Aged 40 to 64 years

• Resident in mainland Portugal or the islands

• Able and willing to provide written informed consent

• Willing to provide stool and blood samples and complete three questionnaires

Locations
Other Locations
Portugal
Gulbenkian Institute for Molecular Medicine, Lisbon
RECRUITING
Lisbon
Contact Information
Primary
Ana S Almeida, PhD
ana.almeida@gimm.pt
+351 217999411
Backup
Madalena Reis
madalena.reis@gimm.pt
+351 217999411
Time Frame
Start Date: 2025-06-02
Estimated Completion Date: 2036-12
Participants
Target number of participants: 300
Treatments
Premenopausal women (self-reported)
Regular menstrual periods, with no signs of menopause yet.
Perimenopausal women (self-reported)
Irregular menstrual periods, presence of some menopausal symptoms, such as hot flashes, mood changes, sleep disturbances, and brain fog.
Menopausal/Postmenopausal women (self-reported)
Absence of menstruation for 12 consecutive months.
Related Therapeutic Areas
Sponsors
Collaborators: Biocodex Microbiota Foundation
Leads: Gulbenkian Institute for Molecular Medicine

This content was sourced from clinicaltrials.gov