Prognostic Significance of Ga-68 FAPI PET Before Immunotherapy in Pleural Mesothelioma
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
It is aimed to evaluate FAP expression and its success in predicting treatment response before immunotherapy used in the treatment of malignant mesothelioma with Ga68 FAPI PET/CT imaging, which allows in vivo evaluation of FAP expression, which is thought to be associated with immunosuppression and resistance to immunotherapy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Having a histopathologically confirmed diagnosis of
• Pleural Mesolthelioma
• Patients scheduled for immunotherapy with anti-PDL-1 and/or anti-CTLA-4 antibodies as first or second line therapy
• Patients who gave informed consent form to participate in the study
Locations
Other Locations
Turkey
Ankara University School of Medicine
RECRUITING
Ankara
Time Frame
Start Date: 2024-04-30
Estimated Completion Date: 2025-04-30
Participants
Target number of participants: 30
Treatments
Experimental: Treatment arm
Patients underwent Ga68 FAPI PET before immunotherapy
Related Therapeutic Areas
Sponsors
Leads: Ankara University
Collaborators: Ankara Yildirim Beyazıt University, Social Sciences University of Ankara, Liv Hospital Ankara