Reducing Dietary Acid With Fruit and Vegetables Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD) Feasibility Trial
Metabolic acidosis is a common problem that occurs with worsening chronic kidney disease. Dietary acid can build up when the kidneys are not working well. This can be associated with a higher risk of worsening kidney function and death. The usual treatment is a medication called sodium bicarbonate which works to balance the acids in the body. The medication however often does not work and causes side effects. Consumption of alkalizing fruit and vegetables may work as a treatment for metabolic acidosis. This trial is being done to see if fruit and vegetables, provided via home delivery, can become a viable management for metabolic acidosis in patients with chronic kidney disease.
• Participant is willing and able to give informed consent for participation in the trial
• Male or Female, aged 18 years or above
• Participants who have an eGFR between 15 and 40 ml/min/1.73m2
• Two consecutive measurements of serum bicarbonate of 14 to 22 mEq/L
• Systolic and diastolic blood pressure \<160/100 mmHg
• Serum potassium \<5.3 mmol/L
• Hemoglobin A1c below ≤ 11%
• Are registered in the nephrology clinic in Winnipeg or Halifax
• Participants are able to communicate in English and provide written informed consent