Does Nerve Block Plus Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hours Better Than Nerve Block Alone?
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• Meet ICHD-3 Migraine Headache Criteria
• Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2
• Nerve block performed with bupivacaine 0.5%
Locations
United States
Texas
University Medical Center of El Paso
RECRUITING
El Paso
Contact Information
Primary
Edward Michelson, MD
edward.michelson@ttuhsc.edu
915 215 4600
Time Frame
Start Date: 2023-09-15
Estimated Completion Date: 2026-01-30
Participants
Target number of participants: 84
Treatments
Experimental: Dexamethasone
single oral dose of dexamethasone (8mg)
Placebo_comparator: Placebo
Single oral dose of placebo pill
Sponsors
Leads: Texas Tech University Health Sciences Center, El Paso