Evaluating the Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines in the Emergency Department
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years or older
• Able to provide informed consent
• English speaking
• Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics
Locations
United States
Illinois
Advocate Christ Medical Center Emergency Department
RECRUITING
Oak Lawn
Contact Information
Primary
Ryan McKillip, MD
ryan.mckillip@aah.org
708-684-6230
Backup
Marc McDowell, PharmD
marc.mcdowell@aah.org
708-684-1078
Time Frame
Start Date: 2025-12-16
Estimated Completion Date: 2027-06
Participants
Target number of participants: 100
Treatments
Experimental: Study Drug
Prochlorperazine 10 mg followed by Magnesium 2 g
Active_comparator: Control Arm
Prochlorperazine 10 mg followed by placebo
Related Therapeutic Areas
Sponsors
Leads: Wake Forest University Health Sciences