The Long Term Efficacy of High Frequency Repetitive Transcranial Magnetic Stimulation on Postural Stability in Parkinsonian Patients.

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Postural instability is one of the cardinal signs in Parkinson's disease (PD). It represents one of the most disabling symptoms in the advanced stages of the disease. It is associated with frequent falls and loss of independence. The aim of the current study is to assess the long term efficacy of high frequency repetitive transcranial magnetic stimulation (rTMS) on improving postural instability in PD patients.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 55
Maximum Age: 70
Healthy Volunteers: f
View:

• All included patients should fulfill the U.K Parkinson's Disease Brain Bank Criteria for idiopathic PD.

• Patients with mild to moderate disease severity according to UPRS and Modified Hoehn and Yahr staging

• Duration of illness from two to five years were included.

• All included patients should be medically and psychologically stable and of adequate cardiac function.

• All included patients should haven't receive any rTMS sessions before.

• Signed consent form should be taken from all included patients.

Locations
Other Locations
Egypt
Faculty of Physical Therapy, Cairo University
RECRUITING
Giza
Contact Information
Primary
Engy BadrEldin S Moustafa, PhD
engybm.saleh@cu.edu.eg
00201099445112
Backup
Engy BadrEldin S Moustafa, PhD
engybm.saleh@yahoo.com
+971506501530
Time Frame
Start Date: 2023-04-23
Estimated Completion Date: 2024-04-28
Participants
Target number of participants: 40
Treatments
No_intervention: G1 ( Conventional Physical Therapy Program group)
Patients in (G1) will be treated by a designed physiotherapy program consisted of aerobic exercise on treadmill, stretching exercise, Proprioceptive neuromuscular facilitation (PNF) techniques, Graduated active exercises, gait training, Reciprocal and weight shifting exercises. The treatment will be conducted three sessions per week, day after day for successive four weeks. The session duration was 40min to 1 hour.
Experimental: G2 ( High Frequency rTMS group)
Patients in (G2) will be treated by high frequency repetitive transcranial magnetic stimulation (HF-rTMS) in addition to the same physiotherapy program as in G1. The treatment will be conducted three sessions per week, day after day for successive four weeks. The session duration for rTMS will be 20-30 minutes, the physiotherapy session will be 40-45 min.
Related Therapeutic Areas
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov