Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
The investigators are investigating the brain activity associated with sensory information in movement disorders in order to improve treatment of these symptoms beyond what is currently available.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 89
Healthy Volunteers: t
View:
• Age \>18 years
• Clinically definite, advanced idiopathic PD based on consensus criteria.
• Normal, or essentially normal, preoperative brain MRI.
• Patient is available for follow-up visits over the length of the study
• Patient has elected to undergo DBS surgery as part of routine care, and subthalamic nucleus (STN) is determined as the appropriate surgical target
• Age \>18 years.
• No diagnosis of PD, other movement disorder, or other significant neurological disease.
Locations
United States
Alabama
The University of Alabama at Birmingham Hospital
RECRUITING
Birmingham
Contact Information
Primary
Zachary Irwin, PhD
zirwin@uabmc.edu
(205) 934-6704
Time Frame
Start Date: 2022-06-08
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 30
Treatments
Deep Brain Stimulation Surgery Patients
The investigators will seek to enroll people with Parkinson's disease (PD) who have been approved for deep brain stimulation surgery (DBS) as part of their routine clinical
Healthy controls
The investigators will seek to enroll a cohort of age- and sex-matched healthy individuals to act as a control group. This group will NOT undergo DBS surgery
Related Therapeutic Areas
Sponsors
Leads: University of Alabama at Birmingham
Collaborators: National Institute of Neurological Disorders and Stroke (NINDS)