Adding Computer-based Cognitive Training to Conventional Rehabilitation Can Affect Postural Stability , Locomotion and Cognition in Parkinson's Disease Patients

Status: Recruiting
Location: See location...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

BACKGROUND: Postural instability and gait abnormalities are cardinal features in Parkinson's disease (PD). It represents one of the most disabling symptoms in the advanced stages of the disease. The purpose of this study was to evaluate the immediate and long-term effects of adding computer-based cognitive training to physical therapy interventions on postural stability, locomotion, and cognitive performance in Parkinson's disease patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 58
Maximum Age: 70
Healthy Volunteers: f
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• Egyptian Parkinson's Disease patients of both sex , all patients fulfilled the U.K Parkinson's Disease Brain Bank Criteria for diagnosis of idiopathic PD.

• The patients' age ranged from 58 to 68 years.

• The duration of illness ranged from two to five years.

• The severity of the disease ranged from mild to moderate disability according to UPDRS motor scores (part III) and Modified Hoehn and Yahr staging (stage 2.5\&3) .

• Cognitive function ranged from 65 to 81 according to Parkinson's Disease-Cognitive Rating Scale (PD-CRS) that indicates mild cognitive impairment.

• The patients with mild balance and gait impairments

• Medically and psychologically stable patients and of adequate cardiac function to adhere to the protocol.

Locations
Other Locations
Egypt
Faculty of Physical Therapy, Cairo University
RECRUITING
Giza
Contact Information
Primary
Engy B Saleh, PhD
engybm.saleh@yahoo.com
00201099445112
Backup
Moshera H. Darwish, PhD
dr.moshera11@yahoo.com
00201015163617
Time Frame
Start Date: 2024-05-23
Estimated Completion Date: 2025-04-20
Participants
Target number of participants: 70
Treatments
Placebo_comparator: Control group (GA)
Patients in control group (GA) will be treated by a designed physiotherapy program consisted of aerobic exercise on treadmill, stretching exercise, Proprioceptive neuromuscular facilitation (PNF) techniques, Graduated active exercises, gait training, Reciprocal and weight shifting exercises for 60 minutes/session, 3 days/week for 8 consecutive weeks
Experimental: Study group (GB)
Patients in (GB) will be treated by computer-based cognitive training for 30 minutes followed by the same physiotherapy program as GA for another 30 minutes. so the whole duration of the treatment session for (GB) is 60 minutes ( half of the session the computerized cognitive training and the other half is for the designed physical therapy program). the whole treatment intervention will be 3 days /week for 8 consecutive weeks.
Related Therapeutic Areas
Sponsors
Leads: Engy Badreldin Saleh Moustafa, PhD

This content was sourced from clinicaltrials.gov