Movement Disorders Clinical Trials

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Controlled, Multicenter Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Multicenter controlled study of sleep disorders in isolated REM Behavior Disorder and Parkinson\'s disease (SOMPARK)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ Common to all groups:

• Age superior 18 years

• Patients who have received complete information about the study from an investigator and who fully consent to participate.

⁃ For Parkinson Disease (PD):

• Patients followed for PD diagnosed according to international criteria for the diagnosis of PD (MDS criteria),

• A MoCA score greater than 20/30

• No treatment with deep brain stimulation.

⁃ For REM Sleep Behavior Disorder (RBD):

• Diagnosis of RBD according to ICSD-3 criteria: presence on polysomnography of an abnormal elevation of muscle tone during REM sleep (more than 18% of REM sleep without chin atonia) and/or the presence of REM sleep behaviors on video-polysomnography,

• Absence of progressive neurodegenerative pathology: absence of diagnostic criteria for PD, multiple system atrophy, or Lewy body dementia.

⁃ For healthy controls:

⁃ \- No neurological or psychiatric disease

Locations
Other Locations
France
CHU de Clermont-Ferrand
RECRUITING
Clermont-ferrand
CHU de Lille
RECRUITING
Lille
CHU de Lyon
RECRUITING
Lyon
CHU de Nantes
RECRUITING
Nantes
CHU de Nîmes
RECRUITING
Nîmes
CHU Pitié Salpêtrière
RECRUITING
Paris
Contact Information
Primary
Isabelle ARNULF, Prof
isabelle.arnulf@aphp.fr
+33 (0)1 42 16 77 04
Time Frame
Start Date: 2025-03-18
Estimated Completion Date: 2028-04
Participants
Target number of participants: 457
Treatments
Experimental: Participants
Study of the sleep with polysomnography during a 2-days stay in hospital. Other exam will be done during the 2 days.
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov

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