Effects of Repetitive Transcranial Magnetic Stimulation on Corticomotor Excitability and Balance Performance in People With Parkinson's Disease
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The study investigates the effects of repetitive transcranial magnetic stimulation on motor cortex excitability, balance, and motor function in patients with Parkinson's disease. Additionally, it further examines the effects of single-session low-frequency and high-frequency repetitive transcranial magnetic stimulation on motor cortex excitability.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 85
Healthy Volunteers: f
View:
• Patients with primary Parkinson's disease
• Age: 40-85 years
• Hoehn and Yahr scale (H\&Y scale) : I-III
• Appropriate prescribed medication, and regular intake for more than 2 weeks
• Can walk more than 10m with or without the use of assistive devices
Locations
Other Locations
Taiwan
Chung Shan Medical Unirversity
RECRUITING
Taichung
Contact Information
Primary
LIU HSIN-HSUAN, PhD
hsuanliu@csmu.edu.tw
04-36098782
Backup
HONG SONG-PING, BSc
th88152714@gmail.com
0952730834
Time Frame
Start Date: 2024-12-16
Estimated Completion Date: 2025-10-30
Participants
Target number of participants: 24
Treatments
Experimental: Group A
Patients in this group first undergo high-frequency rTMS treatment, followed by a two-week rest period, then proceed to low-frequency rTMS after another two-week rest, and finally receive sham stimulation rTMS.~rTMS high-frequency 1Hz 80%RMT rTMS low-frequency 1Hz 80%RMT rTMS sham 10HZ 20%RMT
Experimental: Group B
Patients in this group first undergo low-frequency rTMS treatment, followed by a two-week rest period, then proceed to high-frequency rTMS after another two-week rest, and finally receive sham stimulation rTMS.~rTMS high-frequency 1Hz 80%RMT rTMS low-frequency 1Hz 80%RMT rTMS sham 10HZ 20%RMT
Experimental: Group C
Patients in this group first undergo sham stimulation rTMS treatment, followed by a two-week rest period, then proceed to high-frequency rTMS after another two-week rest, and finally receive low-frequency rTMS.~rTMS high-frequency 1Hz 80%RMT rTMS low-frequency 1Hz 80%RMT rTMS sham 10HZ 20%RMT
Related Therapeutic Areas
Sponsors
Leads: Chung Shan Medical University