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Effects of the Stimulation Site of Trans-spinal Magnetic Stimulation Combined With Transcranial Magnetic Stimulation on Functional Mobility in Individuals With Parkinson's Disease

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This randomized clinical trial aims to compare the effects of two different trans-spinal magnetic stimulation (tsMS) application sites, cervical versus thoracic, when combined with repetitive transcranial magnetic stimulation (rTMS), on functional mobility in individuals with Parkinson's disease (PD). Participants diagnosed with PD will be randomized into two intervention groups (rTMS + cervical tsMS or rTMS + thoracic tsMS) and will undergo 10 treatment sessions. Outcomes will include functional mobility, gait speed, motor function, freeing of gait, balance, quality of life, global perceived improvement and adverse events. The study is expected to identify the most effective tsMS application site to enhance mobility and motor outcomes in PD, contributing to the optimization and standardization of tsMS protocols as an adjunct therapy.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
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Locations
Other Locations
Brazil
Universidade Federal de Pernambuco
RECRUITING
Recife
Contact Information
Primary
Ana Cecília Ribeiro Nascimento, Msc. student
anaceciliaribeiro.n@gmail.com
(81) 99893-6664
Time Frame
Start Date: 2026-01-05
Estimated Completion Date: 2026-12
Participants
Target number of participants: 30
Treatments
Experimental: rTMS + Cervical tsMS
Participants will receive a combined neuromodulation protocol consisting of repetitive transcranial magnetic stimulation (rTMS) applied over the primary motor cortex, followed by trans-spinal magnetic stimulation (tsMS) at the cervical level.
Experimental: rTMS + Thoracic tsMS
Participants will receive a combined neuromodulation protocol consisting of repetitive transcranial magnetic stimulation (rTMS) applied over the primary motor cortex, followed by trans-spinal magnetic stimulation (tsMS) at the thoracic level.
Related Therapeutic Areas
Sponsors
Leads: Universidade Federal de Pernambuco

This content was sourced from clinicaltrials.gov