Multifocal Motor Neuropathy Clinical Trials

Find Multifocal Motor Neuropathy Clinical Trials Near You

An Open-Label, Single-Arm, Phase 1b Study to Evaluate the Effect of Empasiprubart on Nerve Morphology by Ultrasound in Adults With Multifocal Motor Neuropathy

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The main purpose of the study is to evaluate empasiprubart use in adults living with Multifocal Motor Neuropathy (MMN). The researchers will evaluate the effect of empasiprubart on the thickness of the nerves, muscle strength, movement, and on the potential improvement of grip strength of the participants in handling objects. The study consists of an open-label treatment period where all participants will receive empasiprubart intravenously (IV). After the last dose of empasiprubart participants will enter a safety follow-up period for up to 15 months. The total study duration for each participant will be approximately 29 months. More information can be found here: clinicaltrials.argenx.com/empasound

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Is at least 18 years old

• Diagnosed with MMN

• Has an MMN-RODS centile score of ≤90

• Has confirmed nerve thickening in at least 1 nerve per ultrasound measurement

Locations
Other Locations
Georgia
Aversi Clinic LTD
RECRUITING
Tbilisi
Jo Ann Medical Center
RECRUITING
Tbilisi
S. Khechinashvili University Clinic, Ltd.
RECRUITING
Tbilisi
Contact Information
Primary
Sabine Coppieters, MD
clinicaltrials@argenx.com
857-350-4834
Time Frame
Start Date: 2026-07-27
Estimated Completion Date: 2030-04-01
Participants
Target number of participants: 60
Treatments
Experimental: Empasiprubart IV
Participants receive empasiprubart IV
Related Therapeutic Areas
Sponsors
Leads: argenx

This content was sourced from clinicaltrials.gov

Similar Clinical Trials

We couldn't find any related articles check for more on the main search page.