Multiple Myeloma Clinical Trials

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Moving Forward With Myeloma: A Lifestyle Intervention for Individuals With Multiple Myeloma

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this project is to evaluate the impact of a 16-week lifestyle program that promotes changes in eating and exercise patterns. The main questions the study will answer are: Do improvements in eating and exercise patterns lead to improved physical function, quality of life and blood biomarkers of biologial aging among individuals with multiple myeloma? Participants will complete study activities 3-4 times during the study. 1. In-person assessment to measure physical function, height/weight, body composition, and includes a blood draw 2. Surveys completed online or on paper at home

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adult (≥ 18 years)

• Diagnosed with MM at least one year prior to study enrollment

• Has access to a cell phone

• Be deemed clinically stable by their physician guided by the following:

‣ no near-term changes in planned myeloma-directed therapy anticipated. (e.g., patient who is 3 months from autologous stem cell transplant just starting on maintenance lenalidomide is eligible since maintenance is planned therapy following transplant)

⁃ no new significant myeloma symptoms (e.g., fractures) meriting changes in anti-neoplastic therapies; AND

⁃ stable performance status (ECOG 0-2)

• No reports of severe pain \> Grade 3 \[defined by the NCI CTCAE as tumor, neurologic, bone, or other pain interfering with self-care ADLs (bathing, dressing, toileting, continence, feeding)\].

• Able to participate in moderate PA and strength training per clinician approval and confirmed by participant

• Able to understand and willing to sign a written informed consent document

• English proficient for reading and writing

Locations
United States
Illinois
Loyola University Chicago
RECRUITING
Maywood
Wisconsin
Medical College of Wisconsin
RECRUITING
Milwaukee
Contact Information
Primary
Melinda Stolley, PhD
mstolley@mcw.edu
(312)735-6044
Time Frame
Start Date: 2026-01-30
Estimated Completion Date: 2030-02-28
Participants
Target number of participants: 184
Treatments
Experimental: Immediate Intervention
16-session intervention that facilitates changes in nutrition and physical activity behaviors to promote improvements in physical function, Patient Reported Outcomes, body composition and general health. The intervention targets plant-based eating, increasing physical activity and strength training.
Active_comparator: Waitlist control
Participants will be asked to maintain their behavior over the 16 week waitlist period and will receive weekly text message relating positive messages unrelated to lifestyle.
Related Therapeutic Areas
Sponsors
Collaborators: Loyola University Chicago, National Cancer Institute (NCI)
Leads: Medical College of Wisconsin

This content was sourced from clinicaltrials.gov