Multiple Myeloma Clinical Trials

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A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of the LVIVO-TaVec200 Product in the Treatment of Relapsed/Refractory Multiple Myeloma

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

This is a prospective, single-arm, open-label dose-escalation clinical study to evaluate LVIVO-TaVec200 in the treatment of relapsed/refractory multiple myeloma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Subjects voluntarily participate in clinical studies; Fully informed of this study and signed informed consent; Informed consent form must be obtained prior to initiation of any study-related tests or procedures that are not part of the standard treatment for the subject's disease; Good compliance and cooperation with follow-up.

• Age ≥ 18 years.

• Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

• Has measurable lesions

• Relapsed and/or refractory multiple myeloma

• Life expectancy≥ 3 months

• Clinical laboratory values meet screening visit criteria

• Adequate organ function.

Locations
Other Locations
China
The First Affiliated Hospital with Nanjing Medical University
RECRUITING
Nanjing
Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
NOT_YET_RECRUITING
Shanghai
The Second Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITING
Xi’an
The Affiliated Hospital of XUZHOU Medical University
NOT_YET_RECRUITING
Xuzhou
Henan Cancer Hospital
NOT_YET_RECRUITING
Zhengzhou
Contact Information
Primary
Lijuan Chen
chenljb@126.com
025-68306091
Backup
Xuxing Shen
ruxiaoguo1992@163.com
025-68306091
Time Frame
Start Date: 2025-12-10
Estimated Completion Date: 2029-03-31
Participants
Target number of participants: 36
Treatments
Experimental: LVIVO-TaVec200 product
Each subject will be given a single-dose LVIVO-TaVec200 product infusion at each dose level
Related Therapeutic Areas
Sponsors
Collaborators: Nanjing Legend Biotech Co.
Leads: The First Affiliated Hospital with Nanjing Medical University

This content was sourced from clinicaltrials.gov