Randomized Controlled Trial of MIND Diet for Neuroprotection and Symptom Management in MS

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study will assess the impact of a MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet on brain health and MS symptoms. Participants will be randomly assigned to one of two arms: the diet intervention arm or the continue current diet/control arm. Participants randomized to the dietary intervention arm will change their diet to follow a MIND dietary pattern for one year; diet-related education and programming is provided to support this change. Participants randomized to the continue/control arm will be asked to continue their current dietary habits, without major change for one year; multiple sclerosis (MS) MS-related related education and programming (unrelated to diet) is provided. All participants will be asked to provide blood \& stool samples and to complete online questionnaires \& three in-person assessments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Ages 18-70 years, inclusive

• MS diagnosis, on any treatment (including no treatment)

• MIND diet score of ≤8 at baseline

• NfL parameters determined by age

Locations
United States
New York
Mount Sinai Hospital
RECRUITING
New York
Contact Information
Primary
Claire E Wigley, Bsc, BSPH
claire.wigley@mssm.edu
(212) 241-3759
Backup
Susan Filomena
susan.filomena@mssm.edu
212-241-3841
Time Frame
Start Date: 2025-05-12
Estimated Completion Date: 2029-04-30
Participants
Target number of participants: 100
Treatments
Experimental: MIND Diet
Participants randomized to the intervention arm will change their dietary patterns to adhere to the MIND diet for one year after randomization.
Placebo_comparator: Continue Diet
Participants randomized to the control arm will continue their current dietary habits, without major changes, for one year after randomization. Participants will not receive diet education in small group.
Related Therapeutic Areas
Sponsors
Leads: Icahn School of Medicine at Mount Sinai

This content was sourced from clinicaltrials.gov

Similar Clinical Trials