Investigation of Inflammation Using [18F]FZTA
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
This study involves a Positron Emission Tomography (PET) scan using a new investigational radioactive tracer, \[18F\]-FZTA, to detect inflammation in the brain. The tracer will be tested in healthy younger adults and individuals with Multiple Sclerosis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Male or female, any race
• Age ≥ 18 years
• Capable of providing written informed consent for volunteering to undergo research procedures.
• Healthy volunteer or volunteer with a diagnosis of MS established using the revised McDonald criteria (2017)
Locations
United States
Missouri
Washington University in St. Louis
RECRUITING
St Louis
Contact Information
Primary
Jayashree Rajamanickam
jayashree.r@wustl.edu
314-273-6140
Backup
Kelley Jackson
kelleyj@wustl.edu
314 362 3613
Time Frame
Start Date: 2025-08
Estimated Completion Date: 2029-12
Participants
Target number of participants: 80
Treatments
Healthy participants
Healthy participants will receive a single intravenous bolus injection of 7 ± 20% milliCurie (mCi) of the investigational radiotracer \[18F\]-FZTA. Participants will then undergo \[18F\]-FZTA PET scan.
Participants with Multiple Sclerosis
Participants with Multiple Sclerosis will receive a single intravenous bolus injection of 7 ± 20% milliCurie (mCi) of the investigational radiotracer \[18F\]-FZTA. Participants will then undergo a brain \[18F\]-FZTA PET scan
Related Therapeutic Areas
Sponsors
Leads: Washington University School of Medicine