Multiple Sclerosis (MS) Clinical Trials

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Short Sprint Interval Training as an Effective Exercise Strategy for People With Multiple Sclerosis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn whether a short sprint interval training protocol on a cycle ergometer can improve physical function, walking, muscle strength, exercise capacity, fatigue, cognitive processing speed, and patient-reported outcomes in people with multiple sclerosis. The main questions it aims to answer are: 1. Does short sprint interval training improve walking performance, lower-limb coordination, muscle strength, exercise capacity, fatigue, and cognitive processing speed in people with multiple sclerosis? 2. How do participants respond to short sprint interval training in terms of heart rate, power, cadence, perceived exertion, and affective valence? 3. What adverse events or unintended effects, if any, occur during the intervention? Researchers will compare short sprint interval training with usual physical activity to see if this exercise program improves physical, cognitive, and patient-reported outcomes. Participants will: 1. Be randomly assigned to either a short sprint interval training group or a usual physical activity group. 2. Complete assessments before and after the 2-week training period. 3. Continue their usual physical activity if they are assigned to the control group. 4. Complete 6 supervised exercise sessions over 2 weeks if they are assigned to the short sprint interval training group. 5. During each exercise session, perform short 5-second high-intensity cycling sprints on a recumbent cycle ergometer, separated by recovery periods. 6. Complete walking, strength, stepping, calf endurance, fatigue, and cognitive processing speed assessments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Diagnosis of multiple sclerosis according to the revised McDonald criteria; Expanded Disability Status Scale score 0-3.5.

• Age 18-65 years.

• No multiple sclerosis relapse or exacerbation in the previous month.

Locations
Other Locations
Spain
Ule Motion Lab
RECRUITING
Ponferrada
Contact Information
Primary
Daniel Alexandre Boullosa Álvarez
dboua@unileon.es
+34 987 29 30 00
Time Frame
Start Date: 2026-09
Estimated Completion Date: 2026-10
Participants
Target number of participants: 40
Treatments
Experimental: Short Sprint Interval Training Intervention Group
No_intervention: Usual Physical Activity Control Group
Participants in this arm will not receive any intervention and will be asked to continue their usual physical activity during the 2-week study period.
Related Therapeutic Areas
Sponsors
Collaborators: University of Leon, Hasselt University, El Bierzo Hospital, Sil Multiple Sclerosis Association
Leads: Universidad de León

This content was sourced from clinicaltrials.gov