Evaluating Task-Oriented Exercise Effects on Walking Function and the Central Nervous System in People With Multiple Sclerosis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A growing body of work suggests that regular exercise can support symptom management and improve physical function for people living with multiple sclerosis (MS). Although exercise is known to be beneficial for managing many symptoms related to MS, its effects on the central nervous system, and whether these effects change with different types of exercise, are not well understood. Here, the investigators have designed a clinical trial that compares the effects of distinct exercise protocols on aspects of physical function, physical fitness, and central nervous system function. This research will be the first to compare the effects of different types of exercise on central nervous system changes in people with MS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• diagnosis of progressive MS by a neurologist

• physician clearance for exercise

• a Patient-Determined Disease Steps (PDSS) score between 3 and 7 (i.e., moderate motor disability)

• a Timed 25-Foot Walk (T25-FW) test time \> 6.0 s.

Locations
Other Locations
Canada
University of Regina
RECRUITING
Regina
Contact Information
Primary
Cameron Mang, PhD
cameron.mang@uregina.ca
306-585-4066
Time Frame
Start Date: 2022-06-15
Estimated Completion Date: 2025-04-30
Participants
Target number of participants: 69
Treatments
Experimental: Exercise Group 1
The intervention will focus on mobility and balance.
Active_comparator: Exercise Group 2
This intervention will focus on physical fitness.
Sham_comparator: Exercise Group 3
This intervention will focus on flexibility, range of motion, and muscle tone.
Related Therapeutic Areas
Sponsors
Collaborators: Saskatchewan Health Research Foundation, First Steps Wellness Centre, University of Saskatchewan
Leads: University of Regina

This content was sourced from clinicaltrials.gov