Multiparametric Clinical, Radiological, Neuropsychological, and Neurophysiological Assessment to Investigate Prognostic Factors for Disease Evolution and Treatment Response in MS: a Prospective Study.
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This prospective study combining non conventional MRI techniques, neuropsychological screening tools, and a neurophysiological work-up using a sensitive and validated battery, will evaluate the predictive value of these measures and will explore the changes of the cognitive scores from baseline.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: f
View:
• active MS, according to the Lublin criteria
• disease duration \< 10 years before initiating or changing a disease-modifying therapies,
• relapse- and steroid-free for at least 1 month before MRI acquisition
• between 18-50 years old
• having given informed consent
• with no significant comorbidity other than MS or substance abuse that could interfere with cognitive performances
Locations
Other Locations
Belgium
CHU UCL Namur site Godinne
RECRUITING
Yvoir
Contact Information
Primary
Frédéric London, MD
frederic.london@chuuclnamur.uclouvain.be
+3282413345
Time Frame
Start Date: 2022-06-06
Estimated Completion Date: 2026-06-06
Participants
Target number of participants: 50
Treatments
Other: RRMS patients
RRMS patients initiating a new DMT
Related Therapeutic Areas
Sponsors
Collaborators: Saint-Luc University Hospital
Leads: University Hospital of Mont-Godinne