Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis
Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY
The purpose of this project is to study genetic determinants of mitochondrial impairment in primary progressive multiple sclerosis. Specific aims are: 1) identify mitochondrial-related pathways, inherited and somatic mitochondrial DNA mutations associated to primary progressive multiple sclerosis, 2) functionally assess the identified genetic alterations.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients affected by primary progressive or relapsing remitting multiple sclerosis
• Patient able to provide informed consent
Locations
Other Locations
Italy
ASST della Valle Olona - Ospedale di Gallarate
RECRUITING
Gallarate
IRCCS San Raffaele
RECRUITING
Milan
Contact Information
Primary
Federica Esposito
esposito.federica@hsr.it
0226437833
Time Frame
Start Date: 2021-09-20
Estimated Completion Date: 2025-05-30
Participants
Target number of participants: 140
Treatments
Primary Progressive multiple sclerosis
patients affected by primary progressive multiple sclerosis
Relapsing Remitting multiple sclerosis
patients affected by primary progressive multiple sclerosis
Related Therapeutic Areas
Sponsors
Collaborators: Azienda Socio Sanitaria Territoriale della Valle Olona
Leads: IRCCS San Raffaele