Effect of Galvanic Vestibular Stimulation on Cortical Excitability and Hand Dexterity in Multiple Sclerosis Patients

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

This study will be conducted to investigate the following: 1. The impact of implementing GVS in MS rehabilitation on cortical excitability. 2. The influence of GVS on upper limb function in patients diagnosed with MS. Patients will be randomly assigned to a control group (Conventional Physical Therapy program = CPT) and a study group (Galvanic Vestibular Stimulation = GVS in addition to the conventional program) subsequently. CPT will perform moderate intensity aerobic training (arm ergometer) and task oriented hand manipulation training, while GVS will receive Galvanic Vestibular Stimulation will be added to the conventional physical Therapy program.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 45
Healthy Volunteers: f
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• Patients with ataxic RRMS type of both genders will be recruited. The last MS relapse occurred at least 3 months prior to the study.

• Patients' age will range from 20 to 45 years old.

• Ambulant Patients who meet the level less than or equal to 5 on EDSS will be recruited.

• Patients' score on Mini Mental State Examination should be \> 26.

• Mild or no spasticity (grade 1 or 1+) according to Modified Ashworth Scale.

• All patients must at least hold Primary stage certificate of education from one of the Egyptian educational authorities.

• All patients can independently sign consent form

Locations
Other Locations
Egypt
Cairo University
RECRUITING
Cairo
Time Frame
Start Date: 2023-09-03
Estimated Completion Date: 2025-12
Participants
Target number of participants: 40
Treatments
Experimental: GVS group
Galvanic Vestibular Stimulation in addition to the Conventional Physical Therapy program of moderate intensity aerobic training on cyclic ergometer for upper limb and task oriented training for hand dexterity.
Active_comparator: CPT group
Conventional Physical Therapy program of moderate intensity aerobic training on cyclic ergometer for upper limb and task oriented training for hand dexterity.
Related Therapeutic Areas
Sponsors
Leads: Cairo University

This content was sourced from clinicaltrials.gov