Treatment of Supine Hypertension in Autonomic Failure with Continuous Positive Airway Pressure
Status: Recruiting
Location: See location...
Intervention Type: Drug, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• Patients with autonomic failure and with supine hypertension from all races
Locations
United States
Tennessee
Autonomic Dysfunction Center/ Vanderbilt University Medical Center
RECRUITING
Nashville
Contact Information
Primary
Bonnie K Black, RN
autonomics@vumc.org
615-343-6862
Backup
Luis E Okamoto, MD
autonomics@vumc.org
(615) 936-6119
Time Frame
Start Date: 2017-09-21
Estimated Completion Date: 2026-12-21
Participants
Target number of participants: 12
Treatments
Placebo_comparator: Placebo pill or patch or sham CPAP
Placebo pill or patch or sham CPAP
Active_comparator: CPAP (continuous positive airway pressure)
Continuous positive airway pressure during the night
Authors
Andre Diedrich, Italo Biaggioni
Related Therapeutic Areas
Sponsors
Leads: Vanderbilt University Medical Center