An Open-label, Prospective, Single-arm Study Assessing the Efficacy and Safety of Rozanolixizumab in Adult Chinese Participants With Generalized Myasthenia Gravis

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The purpose of the study is to assess the clinical efficacy of rozanolixizumab in adult Chinese participants with generalized myasthenia gravis (gMG) in the first Treatment Cycle.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Study participant must be ≥18 years of age at the time of signing the informed consent form (ICF)

• Study participant has documented diagnosis of generalized myasthenia gravis (gMG) at the Screening Visit based on study participant's history and supported by previous evaluation

• Study participant has a confirmed positive record of autoantibodies against acetylcholine receptor (AChR) or muscle-specific kinase (MuSK) documented in the medical history at the Screening Visit

• Study participant has Myasthenia Gravis Foundation of America (MGFA) Clinical Classification II to IV at Screening Visit.

• Study participant with a myasthenia gravis-activities of daily living (MG-ADL) score of at least 3 points from non-ocular symptoms and a quantitative myasthenia gravis (QMG) score of at least 11 at the Screening and Baseline visits in the first Treatment Cycle.

• Study participant is considered for additional treatment by the investigator

• Body weight ≥35kg at the Screening Visit

Locations
Other Locations
China
Mg0033 20348
RECRUITING
Fuzhou
Mg0033 20172
RECRUITING
Shanghai
Contact Information
Primary
UCB Cares
ucbcares@ucb.com
+18445992273
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2027-10-15
Participants
Target number of participants: 40
Treatments
Experimental: Rozanolixizumab
Participants will receive 6 dose per cycle of subcutaneous infusion of rozanolixizumab
Related Therapeutic Areas
Sponsors
Leads: UCB Biopharma SRL

This content was sourced from clinicaltrials.gov