Patient Observation With Environmental and Wearable Sensors in Myasthenia Gravis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

This observational study seeks to investigate the underlying processes of myasthenia gravis by employing multimodal monitoring techniques. By integrating digital biomarkers alongside clinical monitoring, we aim to enhance the detection of disease activity and establish correlations between digital measures, clinical scores and various questionnaires including sores on quality of life, sleep quality or activities of daily living. Primarily including patients treated with newly approved drugs, it aims at improving and monitoring the efficacy and safety of treatment and allowing a more individualized treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Formal diagnosis of generalized Myasthenia Gravis, with at least one of the following criteria:

‣ Response to oral or intravenous administration of an acetylcholinesterase inhibitor

⁃ Evidence of pathological decrement/ elevated jitter

⁃ Evidence of Myasthenia Gravis-typical antibody (AChR, LRP4, MuSK, Titin) OR other diagnosed Myasthenic Syndrome

• Age ≥ 18

• Usage of Smartphone with Android 8.1 (or higher) or IOS12.3 (or higher)

• Able to provide informed consent, based on investigator´s judgment

Locations
Other Locations
Germany
Heinrich-Heine University, Duesseldorf
RECRUITING
Düsseldorf
Contact Information
Primary
Marc Pawlitzki, PD Dr. med.
neuro-trials@med.uni-duesseldorf.de
+49211 8117887
Time Frame
Start Date: 2024-05-02
Estimated Completion Date: 2025-10-31
Participants
Target number of participants: 20
Treatments
Myasthenic Syndromes Observational Cohort
Cohort to be characterized via clinical, serological and digital observations
Sponsors
Leads: Heinrich-Heine University, Duesseldorf

This content was sourced from clinicaltrials.gov