Characterization of Transcutaneous Spinal Cord Stimulation for Enabling Reflex Motor Evoked Responses in Children and Youth With Spina Bifida
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
A study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 18
Healthy Volunteers: f
View:
• Congenital diagnosis of myelomeningocele (MMC)
• Able to follow verbal commands or instructions.
• If female and able to become pregnant, must be willing to use medically-acceptable method of contraception during study participation.
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Julie Block
Block.Julie@mayo.edu
507-255-7393
Time Frame
Start Date: 2025-08-07
Estimated Completion Date: 2030-07
Participants
Target number of participants: 30
Treatments
Experimental: Functional motor training with transcutaneous spinal cord stimulation
Transcutaneous spinal cord stimulation will be delivered to the skin over the lower thoracic and lumbar spine region using adhesive electrodes for ages 5-11 for one multi-hour visit. The effects of stimulation will be recorded via electrophysiological and biomechanical metrics described within the outcomes measures.
Experimental: Extended functional motor training with transcutaneous spinal cord stimulation
An extended functional training arm for a subset of 10 subjects, ages 12-18, in which they will receive up to twelve multi-hour sessions of a therapeutic neuromuscular strengthening intervention within a 6 week period.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic