• Pathologically diagnosed with recurrent nasopharyngeal carcinoma;

• Stage rT1 or rT2(superficial parapharyngeal space, distance to internal carotid artery \>5mm)or rT3 (confined to the bottom wall of the sphenoid sinus),according to AJCC 8th edition;

• Cervical lymph node metastasis can be controlled locally

• Age 18 to 75 years;

• Without distant metastasis;

• Informed consent forms signed;

• ≥6months from the accomplishment of radiation to recurrence

• previously radiotherapy for only 1 course;

• ECOG score 0-2 and can tolerate chemotherapy and immunotherapy

⁃ Sufficient organ function;

⁃ Undergone endoscopic surgery with negative pathological margin;