• The legal guardian of the subject voluntarily signed the written informed consent, and the subject over 8 years is required to sign the written informed consent voluntarily.

• Patients with myopia aged 6 to 12 years, including cut-offs.

• The equivalent spherical refraction ranges from -1.00 D to -4.00 D (automatic optometry under a cycloplegia condition) in both myopia eyes at inclusion screening.

• The astigmatism of both eyes was ≤ 1.50 D under a cycloplegia condition at inclusion screening.

• The antimetropia (measured by equivalent spherical refraction) is \< 2.00 D at inclusion screening.

• Able to comply with study requirements, attend all study visits (including telephone visits), and be willing to receive random grouping of atropine treatment or placebo.