Effects of Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Drug
Study Type: Observational
SUMMARY
The objective of this study is to better understand the comprehensive integration of both clinical and genetic factors that will help to identify mothers who could be at an increased risk of poor response to opioid substitution and infants at risk of significant neonatal abstinence syndrome (NAS).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Healthy Volunteers: t
View:
• Age greater 18 years
• Currently taking Buprenorphine for Opioid Use Disorder and enrolled in a prenatal opioid maintenance program in the antenatal clinic at IU Health University Hospital.
• Pregnant with single baby
• Planned delivery at Methodist, University or Riley Hospital
Locations
United States
Pennsylvania
UPMC Children's Hospital
RECRUITING
Pittsburgh
Contact Information
Primary
Senthil Sadhasivam, MD, MPH
sadhasivams@upmc.edu
4126474484
Backup
Carly Riedmann, MPH
riedmannca@upmc.edu
4126234147
Time Frame
Start Date: 2018-09-15
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 600
Treatments
Pregnant Mothers with Opioid Use Disorder
Planned recruitment of 200 pregnant (\<16weeks) mothers who have opioid use disorder and are taking buprenorphine
Pregnant Mothers
Planned recruitment of 100 pregnant (\>16weeks) mothers who do not have any history of opioid use disorder.
Authors
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Leads: Senthil Sadhasivam