Intravesical Gentamicin Coupled With Lactobacillus Rhamnosus for Urinary Health- Early Career

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational qualitative study is to learn about the experiences and perspectives of patients with neurogenic lower urinary tract dysfunction (NLUTD) and their caregivers regarding different types of intravesical instillations used for urinary health. The study aims to understand the perceived benefits, challenges, and opportunities related to Lactobacillus-only, gentamicin-only, and combined gentamicin-Lactobacillus instillations. The main question this study seeks to answer is: 1\. Determine patient and caregivers' preferences, and overall experiences regarding intravesical therapeutics for urinary symptoms and UTI Researchers will compare responses from four groups: participants who have used Lactobacillus-only instillations, gentamicin-only instillations, combined gentamicin-Lactobacillus instillations, and caregivers who have experience supporting instillations. Participants will take part in a one-hour semi-structured interview and may be contacted for brief follow-up discussions to clarify findings. Interviews will be audio-recorded, transcribed, and analyzed using qualitative data software to identify themes related to treatment preferences and acceptability.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Criteria for patients:

• Age 18+

• Diagnosis of NLUTD

• Chronic catheter usage (minimum 6 months), either intermittent catheterization or indwelling catheter

• Community-dwelling

• Experience using intravesical Lactobacillus, gentamicin, or combination of the two

⁃ Criteria for caregivers:

• Age 18+

• Care for patient with diagnosis of NLUTD

• Care for patient who has used catheters chronically (minimum 6 months)

• Experience facilitating patients' use of intravesical Lactobacillus, gentamicin, or combination of the two

Locations
United States
Washington, D.c.
Medstar National Rehabilitation Hospital
RECRUITING
Washington D.c.
Contact Information
Primary
Christopher Riegner, MPH
Christopher.R.Riegner@medstar.net
202-892-5857
Backup
Inger Ljungberg, MPH
Inger.H.Ljungberg@medstar.net
202-877-1694
Time Frame
Start Date: 2025-06-19
Estimated Completion Date: 2027-09
Participants
Target number of participants: 60
Related Therapeutic Areas
Sponsors
Collaborators: Congressionally Directed Medical Research Programs
Leads: Medstar Health Research Institute

This content was sourced from clinicaltrials.gov

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