Impact of Activity-Dependent Plasticity on Bladder Function After Pediatric Spinal Cord Injury

Status: Active_not_recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY

Bladder dysfunction is one of the most important factors influencing duration and quality of life in children with spinal cord injury. Effective bladder control comprises a major aspect of a child's life with SCI and is especially challenging due to the rapid changes in a child's physical and cognitive development. Urological consequences secondary to a neurogenic bladder are responsible for many clinical complications post-spinal cord injury, including repeated urinary tract infections, autonomic dysreflexia, lifelong urologic care, and many hospitalizations. Alternative approaches to bladder management that focus on recovery of function and age-appropriate independence are needed. Prior research findings in our lab in adult participants indicate a benefit of locomotor training on bladder function. The purpose of this study is to determine with quantitative unbiased urodynamic outcome measures if locomotor training, provided to children with spinal cord injury, impacts the developing urinary system.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Maximum Age: 18
Healthy Volunteers: t
View:

• Supra-sacral, non-progressive spinal cord injury

• Bladder dysfunction post-injury

Locations
United States
Kentucky
University of Louisville
Louisville
Time Frame
Start Date: 2018-04-26
Completion Date: 2026-06-30
Participants
Target number of participants: 6
Treatments
Locomotor Training
Assessments for bladder function will be conducted pre-training and following 80 sessions of locomotor training. Locomotor training consists of body-weight supported stepping on a treadmill for one hour.
Sponsors
Collaborators: The Leona M. and Harry B. Helmsley Charitable Trust, Kosair Charities, Inc.
Leads: University of Louisville

This content was sourced from clinicaltrials.gov