A Randomized, Double-blind, Multiregional Phase 3 Study of Ivonescimab Combined With Chemotherapy Versus Pembrolizumab Combined With Chemotherapy for the First-line Treatment of Metastatic Non-small Cell Lung Cancer (HARMONi-3)
Status: Recruiting
Location: See all (260) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This is a Phase 3 Randomized, double-blind, Multiregional Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemotherapy for the First-line Treatment of Metastatic Non-small Cell Lung Cancer. The primary endpoint is overall survival and progression free survival assessed by investigator. The key secondary endpoints include response and safety.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years old at the time of enrollment
• Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1
• Expected life expectancy ≥ 3 months
• Metastatic (Stage IV) NSCLC
• Histologically or cytologically confirmed squamous or non-squamous NSCLC
• Recorded measurement of the Tumor Proportion Score (TPS) or Tumor Cells (TC) for PD-L1 expression, irrespective of the PD-L1 expression, prior to randomization
• At least one measurable noncerebral lesion according to RECIST 1.1
• No prior systemic treatment for metastatic NSCLC
Locations
United States
Arkansas
Genesis Cancer and Blood Institute
ACTIVE_NOT_RECRUITING
Hot Springs
University of Arkansas
ACTIVE_NOT_RECRUITING
Little Rock
Arizona
Banner University Medical Center
ACTIVE_NOT_RECRUITING
Phoenix
TMC Healthcare
ACTIVE_NOT_RECRUITING
Tucson
California
LA Cancer Network
ACTIVE_NOT_RECRUITING
Anaheim
The Oncology Institute of Hope & Innovation
ACTIVE_NOT_RECRUITING
Cerritos
Cedar Sinai Medical Center
ACTIVE_NOT_RECRUITING
Los Angeles
University of Southern California (USC)
ACTIVE_NOT_RECRUITING
Los Angeles
Valkyrie Clinical Trials
ACTIVE_NOT_RECRUITING
Los Angeles
Sutter Institute for Medical Research
ACTIVE_NOT_RECRUITING
Sacramento
UC Davis Medical Center
ACTIVE_NOT_RECRUITING
Sacramento
University of California Los Angeles (UCLA)
ACTIVE_NOT_RECRUITING
Santa Monica
Providence Medical Foundation
ACTIVE_NOT_RECRUITING
Santa Rosa
Kaiser Permanente
ACTIVE_NOT_RECRUITING
Vallejo
Colorado
Rocky Mountain Cancer
ACTIVE_NOT_RECRUITING
Lone Tree
Banner MD Anderson Cancer Center at North Colorado Medical Center
ACTIVE_NOT_RECRUITING
Loveland
Connecticut
Hartford Hospital
ACTIVE_NOT_RECRUITING
Hartford
Yale University
ACTIVE_NOT_RECRUITING
New Haven
Florida
Florida Cancer Specialists & Research Institute (FCS)-East
ACTIVE_NOT_RECRUITING
Fort Myers
BioResearch Partner- Hialeah Hospital
ACTIVE_NOT_RECRUITING
Hialeah
Memorial Healthcare System
ACTIVE_NOT_RECRUITING
Hollywood
Cancer Specialists of North Florida
ACTIVE_NOT_RECRUITING
Jacksonville
Mayo Clinic
ACTIVE_NOT_RECRUITING
Jacksonville
Ocala Oncology
ACTIVE_NOT_RECRUITING
Ocala
Cancer Care of Brevard
ACTIVE_NOT_RECRUITING
Palm Bay
Ascension Sacred Heart Health System
ACTIVE_NOT_RECRUITING
Pensacola
Exigent Network
ACTIVE_NOT_RECRUITING
Petersburg
BRCR Medical Center Inc
ACTIVE_NOT_RECRUITING
Plantation
Florida Cancer Specialists & Research Institute (FCS) - North
ACTIVE_NOT_RECRUITING
St. Petersburg
BRCR Medical Center Inc.
ACTIVE_NOT_RECRUITING
Tamarac
Florida Cancer Specialists & Research Institute (FCS)-South
ACTIVE_NOT_RECRUITING
West Palm Beach
Georgia
Central Georgia Cancer Care
ACTIVE_NOT_RECRUITING
Macon
Illinois
Northwestern Memorial Hospital
ACTIVE_NOT_RECRUITING
Chicago
Illinois Cancer Care P.C.
ACTIVE_NOT_RECRUITING
Peoria
Kansas
University of Kansas Cancer Center
ACTIVE_NOT_RECRUITING
Westwood
Kentucky
Baptist Health
ACTIVE_NOT_RECRUITING
Lexington
Massachusetts
Lahey Hospital
ACTIVE_NOT_RECRUITING
Burlington
Maryland
Ascension Saint Agnes Hospital
ACTIVE_NOT_RECRUITING
Baltimore
Sidney Kimmel Comprehensive Cancer Center
ACTIVE_NOT_RECRUITING
Baltimore
Michigan
Trinity Health
ACTIVE_NOT_RECRUITING
Ann Arbor
University of Michigan
ACTIVE_NOT_RECRUITING
Ann Arbor
Henry Ford Hospital
ACTIVE_NOT_RECRUITING
Detroit
Karmanos Cancer Insitute
ACTIVE_NOT_RECRUITING
Detroit
Minnesota
Mayo Clinic
ACTIVE_NOT_RECRUITING
Rochester
Park Nicollet Institute
ACTIVE_NOT_RECRUITING
Saint Paul
Missouri
American Oncology Partners, PA
ACTIVE_NOT_RECRUITING
Kansas City
Washington University St.Louis
ACTIVE_NOT_RECRUITING
St Louis
Montana
St. Vincent Cancer Center
ACTIVE_NOT_RECRUITING
Billings
North Carolina
University of North Carolina
ACTIVE_NOT_RECRUITING
Chapel Hill
Levine Center
ACTIVE_NOT_RECRUITING
Charlotte
Nebraska
University of Nebraska Medical Center (UNMC)
ACTIVE_NOT_RECRUITING
Omaha
New Hampshire
Dartmouth-Hitchcock Medical Center
ACTIVE_NOT_RECRUITING
Lebanon
New York
Memorial Sloan Kettering
ACTIVE_NOT_RECRUITING
New York
Mount Sinai
ACTIVE_NOT_RECRUITING
New York
SUNY Upstate Medical University
ACTIVE_NOT_RECRUITING
Syracuse
Ohio
Oncology Hematology Care (OHC), Inc
ACTIVE_NOT_RECRUITING
Cincinnati
Cleveland Clinic
ACTIVE_NOT_RECRUITING
Cleveland
University Hospitals Case Medical Center
ACTIVE_NOT_RECRUITING
Cleveland
Oregon
Willamette Valley Cancer Institute and Research Center (WVCI)
ACTIVE_NOT_RECRUITING
Eugene
South Carolina
Medical University of South Carolina (MUSC)
ACTIVE_NOT_RECRUITING
Charleston
Prisma Health-Upstate
ACTIVE_NOT_RECRUITING
Greenville
Tennessee
West Cancer Center
ACTIVE_NOT_RECRUITING
Memphis
SCRI-Nashville
ACTIVE_NOT_RECRUITING
Nashville
Texas
Texas Oncology- Austin
ACTIVE_NOT_RECRUITING
Austin
Texas Oncology-Dallas
ACTIVE_NOT_RECRUITING
Dallas
UT Southwestern Medical Center
ACTIVE_NOT_RECRUITING
Dallas
Houston Methodist Hospital
ACTIVE_NOT_RECRUITING
Houston
MD Anderson Cancer Center
ACTIVE_NOT_RECRUITING
Houston
Texas Oncology-San Antonio
ACTIVE_NOT_RECRUITING
San Antonio
Texas Oncology-Tyler
ACTIVE_NOT_RECRUITING
Tyler
University of Texas at Tyler
ACTIVE_NOT_RECRUITING
Tyler
Virginia
Virginia Oncology Associates
ACTIVE_NOT_RECRUITING
Norfolk
Virginia Cancer
ACTIVE_NOT_RECRUITING
Reston
Washington
Swedish Cancer Institute
ACTIVE_NOT_RECRUITING
Seattle
Cancer Care NW Centers
ACTIVE_NOT_RECRUITING
Spokane
Wisconsin
Carbone Cancer Center
ACTIVE_NOT_RECRUITING
Madison
Other Locations
Belgium
az Glorieux
ACTIVE_NOT_RECRUITING
Ronse
CHU UC Louvain Namur
ACTIVE_NOT_RECRUITING
Yvoir
Canada
London Regional (LRCP)
ACTIVE_NOT_RECRUITING
London
Ottawa Cancer Center
ACTIVE_NOT_RECRUITING
Ottawa
Saskatchewan Cancer
ACTIVE_NOT_RECRUITING
Regina
China
Henan University of Science and Technology Affiliated Anyang Cancer Hospital
ACTIVE_NOT_RECRUITING
Anyang
Cancer Hospital Chinese Academy of Medical Science
ACTIVE_NOT_RECRUITING
Beijing
Peking University People's Hospital
ACTIVE_NOT_RECRUITING
Beijing
The Fifth Medical Center of the General Hospital of the Chinese People's Liberation Army
ACTIVE_NOT_RECRUITING
Beijing
Hunan Cancer Hospital Thoracic Medicine 1
ACTIVE_NOT_RECRUITING
Changsha
Hunan Cancer Hospital Thoracic Medicine 2
ACTIVE_NOT_RECRUITING
Changsha
Xiangya Hospital of Central South University
ACTIVE_NOT_RECRUITING
Changsha
Fujian Cancer Hospital
ACTIVE_NOT_RECRUITING
Fuzhou
First Affiliated Hospital of Gannan Medical University
ACTIVE_NOT_RECRUITING
Ganzhou
Guangxi Medical University Cancer Hospital
ACTIVE_NOT_RECRUITING
Guangxi
Fujian Cancer Hospital
ACTIVE_NOT_RECRUITING
Guangzhou
Hainan General Hospital
ACTIVE_NOT_RECRUITING
Haikou
The First Affiliated Hospital,Zhejiang University
ACTIVE_NOT_RECRUITING
Hanzhou
Zhejiang Cancer Hospital
ACTIVE_NOT_RECRUITING
Hanzhou
Harbin Medical University Cancer Hospital
ACTIVE_NOT_RECRUITING
Harbin
The First Affiliated Hospital Of University Of South China
ACTIVE_NOT_RECRUITING
Hengyang
Shandong Cancer Hospital
ACTIVE_NOT_RECRUITING
Jinan
The First Affiliated Hospital of Yangtze University
ACTIVE_NOT_RECRUITING
Jingzhou
Jinhua Municipal Central Hospital
ACTIVE_NOT_RECRUITING
Jinhua
Yunnan Cancer Hospital
ACTIVE_NOT_RECRUITING
Kunming
Gansu Provincial Cancer Hospital
ACTIVE_NOT_RECRUITING
Lanzhou
Linyi People's Hospital
ACTIVE_NOT_RECRUITING
Linyi
Mianyang Central Hospital
ACTIVE_NOT_RECRUITING
Mianyang
Jiangxi Cancer Hospital
RECRUITING
Nanchang
The First Affiliated Hospital of Nanchang University
ACTIVE_NOT_RECRUITING
Nanchang
The First Affiliated Hospital of Guangxi Medical University
ACTIVE_NOT_RECRUITING
Nanning
Nanyang Central Hospital
ACTIVE_NOT_RECRUITING
Nanyang
Ningbo Medical Center Lihuili Hospital
ACTIVE_NOT_RECRUITING
Ningbo
Qingdao Central Hospital
ACTIVE_NOT_RECRUITING
Qingdao
Shengjing Hospital Of China Medical University
ACTIVE_NOT_RECRUITING
Shenyang
The Fourth Hospital of Hebei Medical University
ACTIVE_NOT_RECRUITING
Shijiazhuang
Shanxi Provincial Cancer Hospital
ACTIVE_NOT_RECRUITING
Taiyuan
TaiZhou Hospital Of Zhejiang Province
ACTIVE_NOT_RECRUITING
Taizhou
Beijing Chest Hospital
ACTIVE_NOT_RECRUITING
Tongzhou
Cancer Hospital Affiliated to Xinjiang Medical University
ACTIVE_NOT_RECRUITING
Ürümqi
The first affiliated Hospital of xi'an jiao tong university
ACTIVE_NOT_RECRUITING
Xi'an
The Second Affiliated Hospital of AFMU
ACTIVE_NOT_RECRUITING
Xi'an
Xiangyang Central Hospital
ACTIVE_NOT_RECRUITING
Xiangyang
Fudan University Shanghai Cancer Center
ACTIVE_NOT_RECRUITING
Xuhui
Shanghai Chest Hospital
ACTIVE_NOT_RECRUITING
Xuhui
The Affiliated Hospital of Xuzhou Medical University
ACTIVE_NOT_RECRUITING
Xuzhou
The Affiliated Hospital of Xuzhou Medical University
ACTIVE_NOT_RECRUITING
Xuzhou
Shanghai Pulmonary Hospital
ACTIVE_NOT_RECRUITING
Yangpu
Fu Yang People's Hospital
ACTIVE_NOT_RECRUITING
Yangzhou
The Second Affiliated Hospital Zhejiang University School of Medicine
ACTIVE_NOT_RECRUITING
Zhejiang
Henan Cancer Hospital
ACTIVE_NOT_RECRUITING
Zhengzhou
France
Centre Hospitalier Regional Universitaire (CHRU) Brest
ACTIVE_NOT_RECRUITING
Brest
Centre Hospitalier Universitaire (CHU) de Caen
ACTIVE_NOT_RECRUITING
Caen
Unicancer - Centre François Baclesse (CFB)
ACTIVE_NOT_RECRUITING
Caen
Centre Hospitalier Intercommunal de Creteil (CHIC
ACTIVE_NOT_RECRUITING
Créteil
Centre de Cancérologie de la Sarthe
ACTIVE_NOT_RECRUITING
Le Mans
Hopital Nord
ACTIVE_NOT_RECRUITING
Marseille
Centre Hospitalier Universitaire de Montpellier (CHU Montpellier)
ACTIVE_NOT_RECRUITING
Montpellier
Institut Curie
ACTIVE_NOT_RECRUITING
Paris
Centre Hospitalier Lyon-Sud
ACTIVE_NOT_RECRUITING
Pierre-bénite
Centre Hospitalier (Intercommunal) De Cornouaille Quimper
ACTIVE_NOT_RECRUITING
Quimper
Centre Hospitalier Universitaire (CHU) de Rennes
ACTIVE_NOT_RECRUITING
Rennes
Institut de Cancérologie de l'Ouest
ACTIVE_NOT_RECRUITING
Saint-herblain
Institut de cancérologie Strasbourg Europe (ICANS)
ACTIVE_NOT_RECRUITING
Strasbourg
Centre Hospitalier Regional et Universitaire de Tours
ACTIVE_NOT_RECRUITING
Tours
Gustave Roussy Oncologie Médical
ACTIVE_NOT_RECRUITING
Villejuif
Germany
Klinikum Esslingen GmbH
ACTIVE_NOT_RECRUITING
Esslingen Am Neckar
Krankenhaus Nordwest GmbH
ACTIVE_NOT_RECRUITING
Frankfurt
Asklepios Klinik Gauting GmbH
ACTIVE_NOT_RECRUITING
Gauting
Universitaetsklinikum Giessen und Marburg
ACTIVE_NOT_RECRUITING
Giesen
Universitaetsklinikum Heidelberg (UKHD)
ACTIVE_NOT_RECRUITING
Heidelberg
Universitaetsklinikum Jena
ACTIVE_NOT_RECRUITING
Jena
Klinikverbund Allgaeu - Klinikum Kempte
ACTIVE_NOT_RECRUITING
Kempten
Universitätsklinikum Schleswig-Holstein
ACTIVE_NOT_RECRUITING
Lübeck
München Klinik gGmbH
ACTIVE_NOT_RECRUITING
Munich
Greece
General Hospital of Athens
ACTIVE_NOT_RECRUITING
Athens
General Hospital of Athens Alexandra
ACTIVE_NOT_RECRUITING
Athens
Henry Dunant Hospital Center
ACTIVE_NOT_RECRUITING
Athens
Interbalkan Medical Center of Thessaloniki
ACTIVE_NOT_RECRUITING
Athens
Metropolitan General Hospital
ACTIVE_NOT_RECRUITING
Athens
Olympion Hospital
ACTIVE_NOT_RECRUITING
Pátrai
University General Hospital of Patras
ACTIVE_NOT_RECRUITING
Pátrai
Galenos General Clinic
ACTIVE_NOT_RECRUITING
Thessaloniki
George Papanikolaou General Hospital of Thessaloniki
ACTIVE_NOT_RECRUITING
Thessaloniki
Ireland
Beaumont Hospital
ACTIVE_NOT_RECRUITING
Dublin
St. James's Hospital (SJH)
ACTIVE_NOT_RECRUITING
Dublin
Galway Univeristy Hospitals
ACTIVE_NOT_RECRUITING
Galway
Italy
Azienda Ospedaliero Universitaria delle Marche
ACTIVE_NOT_RECRUITING
Ancona
Centro di Riferimento Oncologico di Aviano
ACTIVE_NOT_RECRUITING
Aviano
Azienda Ospedaliera Istituti Ospitalieri di Cremona
ACTIVE_NOT_RECRUITING
Cremona
Istituto Europeo di Oncologia (IEO)
ACTIVE_NOT_RECRUITING
Genova
Ospedale San Luca
ACTIVE_NOT_RECRUITING
Lucca
Azienda Socio Sanitaria Territorilae de Mantova (ASST Mantova)
ACTIVE_NOT_RECRUITING
Mantua
Fondazione IRCCS - Istituto Nazionale dei Tumori - Milano
ACTIVE_NOT_RECRUITING
Milan
Istituto Europeo di Oncologia (IEO)
ACTIVE_NOT_RECRUITING
Milan
Fondazione IRCCS San Gerardo dei Tintori
ACTIVE_NOT_RECRUITING
Monza
Universita degli Studi della Campania Luigi Vanvitelli
ACTIVE_NOT_RECRUITING
Naples
Fondazione IRCCS Policlinico San Matteo
ACTIVE_NOT_RECRUITING
Pavia
Azienda Sanitaria Territoriale Pesaro Urbino (AST PU)
ACTIVE_NOT_RECRUITING
Pesaro
Ospedale P. Pederzoli
ACTIVE_NOT_RECRUITING
Peschiera Del Garda
Istituti Fisioterapici Ospitalieri (IFO)
ACTIVE_NOT_RECRUITING
Roma
Azienda Ospedaliera Universitaria Senese - Istituto Toscano Tumori
ACTIVE_NOT_RECRUITING
Siena
Ospedale G.B. Rossi Borgo Roma
ACTIVE_NOT_RECRUITING
Verona
Japan
Fujita Health University Hospital
RECRUITING
Aichi
National Hospital Organization Kyusyu Medical Center
RECRUITING
Fukuoka
Hirosaki University Hospital
RECRUITING
Hirosaki
Hiroshima University Hospital
RECRUITING
Hiroshima
Hakodate Goryoukaku Hospital
RECRUITING
Hokkaido
National Hospital Organization - Hokkaido Cancer Center
RECRUITING
Hokkaido
Nara Medical University Hospital
RECRUITING
Kashihara
Shinshu University Hospital
RECRUITING
Matsumoto
Sendai Kousei Hospital
RECRUITING
Miyagi
Okayama University Hospital
RECRUITING
Okayama
Kansai Medical University Hospital
RECRUITING
Osaka
Osaka Medical and Pharmaceutical University Hospital (OMPU Hp)
RECRUITING
Osaka
Shizuoka Cancer Center (SCC)
RECRUITING
Shizuoka
National Cancer Center Hospital (NCCH)
RECRUITING
Tokyo
The Cancer institute Hospital
RECRUITING
Tokyo
National Hospital Organization Yamaguchi Ube Medical Center
RECRUITING
Yamaguchi
Kanagawa Cancer Center
RECRUITING
Yokohama
Tottori University Hospital
RECRUITING
Yonago
Mexico
Actualidad Basada en Investigación del Cáncer
ACTIVE_NOT_RECRUITING
Guadalajara
Panamerican Clinical Research S.A de C.V.
ACTIVE_NOT_RECRUITING
Guadalajara
Renati Innovation S.A.P.I. DE C.V.
ACTIVE_NOT_RECRUITING
Guadalajara
Centro de Atención Oncológica Viva
ACTIVE_NOT_RECRUITING
La Paz
Arke SMO S.A DE C.V
ACTIVE_NOT_RECRUITING
Mexico City
Centro de Atención Oncológica Viva
ACTIVE_NOT_RECRUITING
Mexico City
Centro de Investigación Clínica GRAMEL
ACTIVE_NOT_RECRUITING
Mexico City
Health Pharma Professional Research S.A. de C.V.
ACTIVE_NOT_RECRUITING
Mexico City
Althian Clinical Research
ACTIVE_NOT_RECRUITING
Monterrey
Hospital Universitario Dr. José Eleuterio González
ACTIVE_NOT_RECRUITING
Monterrey
I Can Oncology Center
ACTIVE_NOT_RECRUITING
Monterrey
Poland
Centrum Onkologii im. prof. F. Lukaszczyka w Bydgoszczy
ACTIVE_NOT_RECRUITING
Bydgoszcz
Instytut Msf Sp. z o.o.
ACTIVE_NOT_RECRUITING
Lodz
Med Polonia Sp. z o.o. NSZOZ
ACTIVE_NOT_RECRUITING
Poznan
Szpital Specjalistyczny w Prabutach
ACTIVE_NOT_RECRUITING
Prabuty
Wojskowy Instytut Medczny
ACTIVE_NOT_RECRUITING
Warsaw
Serbia
Acibadem Bel Medic General Hospital
ACTIVE_NOT_RECRUITING
Belgrade
Klinicki Centar Srbije
ACTIVE_NOT_RECRUITING
Belgrade
Klinicko Bolnicki Centar (KBC) Bezanijska Kosa
ACTIVE_NOT_RECRUITING
Belgrade
Vojnomedicinska Akademija (VMA)
ACTIVE_NOT_RECRUITING
Belgrade
Institut Za Plucne Bolesti Vojvodine Klinika za pulmolosku onkologiju
ACTIVE_NOT_RECRUITING
Kamenica
Univerzitetski Klinicki Centar Kragujevac
ACTIVE_NOT_RECRUITING
Kragujevac
University Clinical Center Niš
ACTIVE_NOT_RECRUITING
Niš
Spain
Hospital Universitario de Badajoz
ACTIVE_NOT_RECRUITING
Badajoz
Hospital Universitari Germans Trias i Pujol
ACTIVE_NOT_RECRUITING
Badalona
Hospital de la Santa Creu i de Sant Pau
ACTIVE_NOT_RECRUITING
Barcelona
Hospital Universitari Dexeus
ACTIVE_NOT_RECRUITING
Barcelona
Instituto Oncologico Baselga (IOB)
ACTIVE_NOT_RECRUITING
Barcelona
Mi Tres Torres
ACTIVE_NOT_RECRUITING
Barcelona
Vall d'Hebron University
ACTIVE_NOT_RECRUITING
Barcelona
Institut d'Investigacio Biomedica de Girona Dr. Josep Trueta
ACTIVE_NOT_RECRUITING
Girona
Hospital Universitario de Jaén
ACTIVE_NOT_RECRUITING
Jaén
Universidad de Las Palmas de Gran Canaria
ACTIVE_NOT_RECRUITING
Las Palmas De Gran Canaria
Hospital Universitario Lucus Augusti (HULA)
ACTIVE_NOT_RECRUITING
Lugo
Hospital Universitario La Paz
ACTIVE_NOT_RECRUITING
Madrid
Universidad Autonoma de Madrid (UAM)
ACTIVE_NOT_RECRUITING
Madrid
Hospital Regional Universitario de Málaga
ACTIVE_NOT_RECRUITING
Málaga
Clinica Universidad de Navarra (CUN) - Pamplona
ACTIVE_NOT_RECRUITING
Pamplona
H Universitario Virgen Del Rocio
ACTIVE_NOT_RECRUITING
Seville
Hospital Clinico Universitario de Valencia (CHUV)
ACTIVE_NOT_RECRUITING
Valencia
Hospital La Fe Bulevar Sur
ACTIVE_NOT_RECRUITING
Valencia
Hospital Alvaro Cunqueiro (HAC)
ACTIVE_NOT_RECRUITING
Vigo
Sweden
Karolinska University Hospital
ACTIVE_NOT_RECRUITING
Stockholm
Region Gävleborg Gävle Sjukhus Gävle Sjukhus
ACTIVE_NOT_RECRUITING
Uppsala
Turkey
Ankara University Medical Oncology
ACTIVE_NOT_RECRUITING
Ankara
Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research
ACTIVE_NOT_RECRUITING
Ankara
Gazi University Medicine Faculty Hospital
ACTIVE_NOT_RECRUITING
Ankara
Memorial Ankara Hospital
ACTIVE_NOT_RECRUITING
Ankara
SBU Gulhane Egitim ve Arastirma Hastanesi
ACTIVE_NOT_RECRUITING
Ankara
Ege Universitesi Tip Fakultesi Hastanesi
ACTIVE_NOT_RECRUITING
Bornova
Medical Point Gaziantep Hospital
ACTIVE_NOT_RECRUITING
Gaziantep
Istanbul Medeniyet University Prof Dr. Suleyman Yalcin City Hospital
ACTIVE_NOT_RECRUITING
Istanbul
İstanbul University Cerrahpasa Medical
ACTIVE_NOT_RECRUITING
Istanbul
Istinye University Bahceshir Liv Hospital
ACTIVE_NOT_RECRUITING
Istanbul
Memorial Saglik Grubu Bahçelievler Hospital
ACTIVE_NOT_RECRUITING
Istanbul
Izmir Economy University Medical Point İzmir Hospital
ACTIVE_NOT_RECRUITING
Izmir
Kocaeli University Hospital
ACTIVE_NOT_RECRUITING
İzmit
Erciyes University Medical Faculty
ACTIVE_NOT_RECRUITING
Kayseri
Necmettin Erbakan University Meram Medical Faculty Hospital
ACTIVE_NOT_RECRUITING
Meram
Dicle University
ACTIVE_NOT_RECRUITING
Sur
United Kingdom
Leeds Teaching Hospitals NHS
ACTIVE_NOT_RECRUITING
Leeds
St. Bartholomew's hospital
ACTIVE_NOT_RECRUITING
London
The Christie NHS Foundation Trust
ACTIVE_NOT_RECRUITING
Manchester
Contact Information
Primary
Summit Clinical Trial Information
medicalinformation@smmttx.com
1-833-256-0522
Time Frame
Start Date: 2023-10-26
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 1600
Treatments
Experimental: Arm A - Ivonescimab and chemotherapy
Subject will receive ivonescimab and chemotherapy
Active_comparator: Arm B - Pembrolizumab and chemotherapy
Subject will receive pembrolizumab and chemotherapy
Related Therapeutic Areas
Sponsors
Leads: Summit Therapeutics