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Quality Improvement Study of a New Generation of Whole Body PET Scanners

Status: Recruiting
Location: See all (7) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The researchers are doing this study to test the capabilities of a new total-body PET scanner called the Biograph Vision Quadra. The researchers want to learn whether this scanner can produce better PET/CT images and provide more useful imaging information than standard PET/CT scanners.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Eligibility Criteria for objective #1:

• Patients with histologically-confirmed non-small cell lung carcinoma (NSCLC) with a single or multiple lung nodules.

• Patients who are undergoing a planned PET-CT scan at main campus of MSK.

• Patients must be ≥ 18 years old

⁃ Eligibility Criteria for objective #2:

• Patients with disease within the chest, abdomen or pelvis, who could benefit from visualizing the pharmacokinetics of radiotracer uptake within all disease sites simultaneously.

• Patients with metastatic prostate or head and neck cancer.

• Patients with prostate cancer who are undergoing a 68Ga-PSMA or 18F-FDG scan at the main campus of MSK.

• Patients with head and neck cancer who are undergoing a 18F-FDG scan at the main campus of MSK

• Patients must be ≥ 18 years old

⁃ Eligibility Criteria for objective #3:

• Patients with histologically-confirmed cancer from all three groups (lung cancer, head and neck cancer, prostate cancer).

• Patients who are undergoing an 68Ga-PSMA or 18F-FDG or an \[18F\]-fluormisonidazole PET-CT scan at the main campus of MSK.

• Patients willing to return to the MITS clinc for late imaging session between 2 to 6 hours after the PET radiotracer injection. (In current practice, FDG is imaged between 1 and 1.5 hours post injection, and FMISO is imaged between 2.5 and 3 hours post injection)

• Patients must be ≥ 18 years old

Locations
United States
New Jersey
Memorial Sloan Kettering Basking Ridge (Consent Only)
RECRUITING
Basking Ridge
Memorial Sloan Kettering Monmouth (Consent Only)
RECRUITING
Middletown
Memorial Sloan Kettering Bergen (Consent Only )
RECRUITING
Montvale
New York
Memorial Sloan Kettering Suffolk-Commack (Consent Only)
RECRUITING
Commack
Memorial Sloan Kettering Westchester (Consent Only)
RECRUITING
Harrison
Memorial Sloan Kettering Cancer Center
RECRUITING
New York
Memorial Sloan Kettering Nassau (Consent Only)
RECRUITING
Rockville Centre
Contact Information
Primary
Heiko Schoder, MD
schoderh@mskcc.org
212-639-8001
Backup
John Humm, PhD
212-639-7367
Time Frame
Start Date: 2026-06-30
Estimated Completion Date: 2029-06
Participants
Target number of participants: 90
Treatments
Patients with lung, head and neck, and prostate cancer
The only investigational aspect of this quality improvement protocol is the acquisition of additional PET/CT imaging data (e.g. breath-hold, dynamic, and/or delayed acquisition) in patients who are already scheduled to receive a PET/CT scan as part of standard of care or under an existing clinical trial.
Sponsors
Leads: Memorial Sloan Kettering Cancer Center

This content was sourced from clinicaltrials.gov