• Patients with histologically or cytologically proven clinical stages IB, II, and III(N2) NSCLC (according to AJCC version 8) eligible for surgical resection with curative intent. Patients with 2 synchronous NSCLC are allowed.

• Measurable disease, as defined by RECIST v1.1.

• Known PD-L1 expression.

• No known EGFR mutations or ALK fusions.

• Written informed consent and HIPAA obtained from the subject prior to performing any protocol-related procedures.

• Age \> 18 years at time of study entry.

• Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

• No prior therapy for lung cancer

• Adequate organ and bone marrow function as defined below:

‣ Absolute neutrophil count (ANC) ≥1.5 x10(3)/uL

⁃ Platelets ≥75 x10(3)/uL

⁃ Hemoglobin ≥9 g/dL

⁃ Serum creatinine ≤1.5 X upper limit of normal (ULN) OR calculated CrCl ≥50 ml/min (using the Cockcroft-Gault formula).

⁃ Serum total bilirubin ≤1.5 X ULN, except in patients with clinically documented Gilbert's Syndrome where ≤3x the ULN is permitted

⁃ Aspartate aminotransferase (AST)/ Alanine aminotransferase (ALT) ≤3 X ULN

⁃ WOCBP\* must have a negative serum (beta-hCG) at screening.

• \*WOCBP are defined as women who are fertile following menarche until becoming postmenopausal, unless permanently sterile. Permanent sterilization methods include hysterectomy, bilateral salpingectomy, and bilateral oophorectomy.

• \- A postmenopausal state is defined as no menses for 12 months without an alternative medical cause. A high FSH level in the postmenopausal range may be used to confirm a postmenopausal state in women not using hormonal contraception or hormonal replacement therapy. However, in the absence of 12 months of amenorrhea, a single FSH measurement is insufficient to determine the occurrence of a postmenopausal state. The above definitions are according to the CTFG guidance. Pregnancy testing and contraception are not required for women who are post-menopausal or with documented permanent sterilization.

∙ Male study patients with WOCBP partners are required to use condoms unless they are vasectomized or practice sexual abstinence.

∙ Vasectomized partner or vasectomized study patient must have received medical assessment of the surgical success.

∙ Periodic abstinence (calendar, symptothermal, post-ovulation methods), withdrawal (coitus interruptus), spermicides only, and LAM are not acceptable methods of contraception. Female condom and male condom should not be used together.

⁃ WOCBP must agree not to donate eggs (ova, oocytes) for the purposes of assisted reproduction during the entire trial and until 6 months after last treatment.

⁃ All men must agree not to donate sperm during the trial and for 6 months after receiving the last therapy dose.