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Feasibility of a Co-designed PRe-radiotherapy Exercise Programme for People With Stage I-III Non-small Cell Lung cAnCEr: A Single-centre, Single Arm Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other, Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to understand the feasibility of a co-designed, pre-radiotherapy exercise programme for people with stage I-III non-small cell lung cancer. This involves people with lung cancer engaging in 20 minutes exercises sessions performed within the radiotherapy department and immediately before each treatment at a personalised intensity. The main questions it aims to answer are: To understand the acceptability of the exercise programme through monitoring recruitment rates, attendance of the exercise sessions, and adherence to prescribed exercise intensities. Adverse events will also be monitored to understand programme safety. Follow-up qualitative interviews will be conducted with participants, their family members, and health care professionals (HCP) to further explore the acceptability of the exercise programme. In total, participants will be invited to perform twenty, supervised exercise sessions scheduled immediately before each treatment within the radiotherapy department. Each exercise session will be twenty minutes in duration and will be performed on a stationary exercise bike. Regarding exercise intensity, there are four levels which may be prescribed depending on people's exercise history, baseline exercise experience, and personal preference. Participants may progress or regress exercise intensity levels throughout the programme depending on their adherence and preference.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients with clinically or histologically confirmed NSCLC stages 1-3.

• Planned to receive treatment with curative intention radiation as primary treatment.

• Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

• At least 18 years of age.

• Can understand and communicate in English.

• Deemed safe to participate in moderate-intensity exercise and for ECG monitored maximal fitness test through the completion of a medical clearance form by their treating physician.

• Able to provide written and informed consent.

Locations
Other Locations
United Kingdom
Northern Ireland Cancer Centre, City Hospital, BHSCT
RECRUITING
Belfast
Contact Information
Primary
Matthew Peter Beggs, MSc, BSc
mbeggs06@qub.ac.uk
+44 7759264875.
Backup
Gillian Dr Prue, PhD., HCPC, FHEA, MCSP
g.prue@qub.ac.uk
+44 28 9097 2345
Time Frame
Start Date: 2026-06-10
Estimated Completion Date: 2026-12
Participants
Target number of participants: 30
Treatments
Experimental: Pre-Radiotherapy exercise arm
Participants within the experimental arm will participate in the co-designed, pre-radiotherapy exercise programme alongside treatment.
Sponsors
Leads: Queen's University, Belfast

This content was sourced from clinicaltrials.gov

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