Cognition After Obstructive Sleep Apnea (OSA) Treatment Among Native American People (CATNAP)

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This research project will develop and implement a motivational interviewing and electronic messaging intervention to address obstructive sleep apnea (OSA), positive airway pressure (PAP) adherence, and risk of Alzheimer's disease and related dementias in American Indians. The project will work with American Indian Elders, aged 50 years and older, from three Northern Plains Reservations and surrounding communities. A total of 300 American Indian elders with a confirmed OSA diagnosis and prescribed PAP therapy will be randomized to receive usual care consisting of PAP therapy alone (control condition) or usual care plus the culturally informed CATNAP MI component (intervention condition).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: f
View:

• Age 50 years and older

• Self report American Indian or Alaskan Native

• diagnosed with obstructive sleep apnea

• prescribed PAP therapy and have a device

• \*Ability to understand written and spoken English; and

• \*Ability and willingness to follow all study protocols.

Locations
United States
South Dakota
Missouri Breaks Industries Research Inc
RECRUITING
Eagle Butte
Contact Information
Primary
Denise Dillard, PhD
denise.dillard@wsu.edu
206-708-8633
Backup
Madison B Ramos, BA
madison.ramos@wsu.edu
Time Frame
Start Date: 2025-02-06
Estimated Completion Date: 2027-12-01
Participants
Target number of participants: 140
Treatments
Experimental: Intervention Group
The CATNAP MI intervention consists of 3 Motivational Interviewing sessions to address obstructive sleep apnea (OSA), positive airway pressure (PAP) adherence, and risk of Alzheimer's disease and related dementias (ADRD) in American Indians and electronic messaging to support PAP adherence, and usual care. Data will be collected at baseline, 3-months, and 9-months.
No_intervention: Waitlist Control Group
Usual care, consisting of an in-service on how to operate the PAP machine, and a mask fitting to select the most comfortable, effective mask for the individual. After 4-6 weeks of use, the participant will be contacted by Missouri Breaks Durable Medical Equipment to review objective adherence data and address any challenges or barriers to therapy such as treatment-emergent central apneas. Data will be collected at baseline, 3-months, and 9-months.
Sponsors
Collaborators: University of Washington, University of Minnesota, Missouri Breaks Industries Research, Inc.
Leads: Washington State University

This content was sourced from clinicaltrials.gov

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