Evolution of Sleep Quality During the Initiation of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Syndrome: an Exploratory Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Continuous positive airway pressure (CPAP) has a caricatural effect in reducing nocturnal respiratory abnormalities and improving the micro-and macrostructure of sleep. Studies characterizing the improvement of acute sleep parameters after the initiation of CPAP are limited to one or two nights of polysomnographic recording. This is related to the cost of performing these studies with repeated recordings in the laboratory and to the acceptability by patients to perform multiple nights of recordings. Investigators currently have powerful and reliable methods allowing us to carry out nights at home in the patient's ecosystem, in real-life conditions. The characterization of sleep parameters by these methods is equivalent to a polysomnographic recording. These technological innovations will allow us to characterize sleep before the initiation of CPAP treatment during several nights performed at home. Investigators will then be able to characterize the kinetics and stability of the improvement of sleep parameters in patients with obstructive sleep apnea syndrome in whom continuous positive airway pressure is initiated. These data will be original and will serve as exploratory data to judge whether the objective improvement of sleep parameters in the first weeks of treatment is associated with improvement in sleepiness, quality of life, and compliance with treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 65
Healthy Volunteers: f
View:

• Patients newly diagnosed with OSA requiring CPAP treatment

• Patients able to use a mobile application on a smartphone or tablet

• Patients with access to a wi-fi internet connection at home

• Patients agreeing to remote monitoring of CPAP compliance data by the home care provider

• Patients who have signed consent to participate in the study

• Subjects affiliated to a social security

Locations
Other Locations
France
Grenoble Alpes University Hospital
RECRUITING
Grenoble
Contact Information
Primary
Jean Louis Pépin, MD, PhD
JPepin@chu-grenoble.fr
0033 476 768 766
Backup
Marie Joyeux-Faure, PharmD, PhD
MJoyeuxfaure@chu-grenoble.fr
Time Frame
Start Date: 2022-10-03
Estimated Completion Date: 2025-12-03
Participants
Target number of participants: 70
Treatments
Experimental: Technological innovations and CPAP
Patients will be equipped with 4 devices: a Dreem 3 Headband, a pulse oximeter, a continuous glucose sensor, and a pedometer. In parallel they will be equipped by the CPAP at home by Icadom.
Authors
Rita CHERPEC épouse CLIN, Renaud Tamisier, Marie DESTORS, Jean Louis Pépin
Related Therapeutic Areas
Sponsors
Collaborators: Dreem, AGIR à Dom
Leads: University Hospital, Grenoble

This content was sourced from clinicaltrials.gov