Examining Early Intervention Obstructive Sleep Apnea Treatment on Long-Term Outcomes in Veterans With SUD/PTSD in a Residential Treatment Program

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone. This is especially true in residential settings where both disorders are more severe than outpatient settings. Obstructive sleep apnea (OSA) is highly comorbid with both disorders and untreated OSA is associated with worse functional impairment across multiple domains, worse quality of life, worse PTSD, higher suicidal ideation, and higher substance use and relapse rates. Treating OSA with evidence-based positive airway pressure (PAP) in Veterans with SUD/PTSD on a residential unit is a logical way to maximize treatment adherence and treatment outcomes. This study compares OSA treatment while on a SUD/PTSD residential unit to a waitlist control group. The investigators hypothesize that treating OSA on the residential unit, compared to the waitlist control, will have better functional, SUD, and PTSD outcomes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• a Veteran of the U.S. military or Reserve/National Guard member

• at least 18 years of age

• have an AHI 5 per hour

• experienced trauma that occurred in childhood or adulthood; at least one month post-trauma

• have current DSM-5 diagnoses of SUD via SCID-SUD module with a minimum 20 days of substance use in the last 90 days (Timeline Follow-back)

• Full PTSD diagnosis via clinician administered PTSD scale

• are literate in English

• are on the PTSD track of the SARRTP unit

• are capable of giving informed consent

Locations
United States
California
VA San Diego Healthcare System, San Diego, CA
RECRUITING
San Diego
Contact Information
Primary
Peter Colvonen, PhD
peter.colvonen@va.gov
(858) 552-8585
Time Frame
Start Date: 2023-01-02
Estimated Completion Date: 2027-05-31
Participants
Target number of participants: 194
Treatments
Experimental: PAP Treatment on SARRTP Unit
Veterans will receive Positive Airway Pressure device while on the 28-day SARRTP Unit.
No_intervention: Waitlist Control
Veterans will not receive PAP device until after 3-month Follow Up.
Sponsors
Leads: VA Office of Research and Development

This content was sourced from clinicaltrials.gov