Biological and Cognitive Marker of Neurodegeneration in Obstructive Sleep Apnea Patients

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to investigate biomarkers and neurocognitive markers of neurodegenerative processes in obstructive sleep apnea patients. The main questions the study aims to answer are: * Does neurodegeneration assessed by neurobiological markers and neurocognitive test performance exists in obstructive sleep apnea? * Are these neurodegenerative markers are associated with the adherence to clinical prescribed positive airway pressure therapy? Newly diagnosed patients with obstructive sleep apnea will be observed during the use of clinical prescribed positive pressure therapy. Different study related investigations take place before and six months after treatment start. Researchers will compare after six months the group of adherent treatment participants with the non-adherent treatment participants group to investigate if differences in the observed neurobiological or neurocognitive parameters exist.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• newly diagnosed obstructive sleep apnea

• clinical indication for start of positive airwas pressure therapy

• Age older than 18 years

Locations
Other Locations
Germany
Technische Universität Dresden, Universitätsklinikum Dresden
RECRUITING
Dresden
Contact Information
Primary
Tony Sehr, MD
tony.sehr@ukdd.de
+49 351 458 19324
Backup
Moritz D Brandt, MD
moritz.brandt@ukdd.de
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2026-06
Participants
Target number of participants: 136
Treatments
Newly diagnosed sleep apnea patients, starting clinical prescribed positive airway pressure therapy
Related Therapeutic Areas
Sponsors
Leads: Technische Universität Dresden

This content was sourced from clinicaltrials.gov