Targeted Treatment of Obstructive Sleep Apnea With Dronabinol: Proof of Concept and Phase II Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
This is an open-label trial that tests the effectiveness of Dronabinol in treating obstructive sleep apnea (OSA). All participants will take oral Dronabinol for two weeks. Sleep studies will be conducted before and after treatment to measure OSA severity.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 65
Healthy Volunteers: f
View:
• 1\. AHI 15-50 per hour on pre-treatment polysomnography
Locations
United States
Illinois
Jesse Brown VA Medical Center, Chicago, IL
RECRUITING
Chicago
Contact Information
Primary
Bharati Prasad, MD
bharati.prasad@va.gov
(312) 996-8433
Backup
Karen M Lenehan
Karen.Lenehan@va.gov
(312) 569-6343
Time Frame
Start Date: 2025-08-25
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 120
Treatments
Experimental: Single group
Open label Dronabinol treatment for two weeks.
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development
Collaborators: University of Illinois at Chicago