Obstructive Sleep Apnea Clinical Trials

Find Obstructive Sleep Apnea Clinical Trials Near You

The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure. The main questions it aims to answer are: Does sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity? Participants admitted to the hospital with heart failure and fluid overload will take part in this study. Participants will: Use a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care Researchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults aged 18 years or older

• Hospitalized with decompensated heart failure and clinical evidence of fluid overload

• Diagnosis of heart failure (reduced or preserved ejection fraction)

• Clinically indicated for diuretic therapy

• Able to undergo sleep apnea assessment using the WatchPAT device

• Able to provide informed consent

Locations
Other Locations
Israel
Shaare Zedek Medical Center
RECRUITING
Jerusalem
Contact Information
Primary
Itshak Amsalem, MD
itshak1a@gmail.com
+972508229454
Time Frame
Start Date: 2026-01-01
Estimated Completion Date: 2027-06
Participants
Target number of participants: 50
Treatments
Adults With Heart Failure Undergoing Diuresis
Adults hospitalized with heart failure and fluid overload who undergo standard diuretic therapy. Participants are evaluated using sleep monitoring (WatchPAT), neck circumference measurements, and clinical assessments before diuresis (on the first night of hospitalization) and after diuresis, when the treating cardiologist determines that the patient is no longer fluid overloaded.
Related Therapeutic Areas
Sponsors
Leads: Itshak Amsalem

This content was sourced from clinicaltrials.gov