Integrated Treatment for Co-Occurring Opioid Use Disorder and Posttraumatic Stress Disorder

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study will test a therapy intervention, HOPE, for individuals with opioid use disorder and posttraumatic stress disorder. Interested individuals will need to be taking medications for opioid use disorder (e.g., suboxone, naltrexone, methadone). Interested participants will complete a 10-12 week therapy, and be asked to complete surveys.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Any gender; any race or ethnicity; aged 18-70 years old.

• English-speaking

• Meet DSM-5 diagnostic criteria for OUD.

• Meet DSM-5 diagnostic criteria for PTSD and have some memory of their index traumatic event.

• Must be maintained on a stable dose of medication for OUD for at least 1 month.

• Participants taking psychotropic medications will be required to be maintained on a stable dose for at least 1 month before study initiation.

Locations
United States
South Carolina
Medical University of South Carolina
RECRUITING
Charleston
Contact Information
Primary
Tanya C Saraiya, Ph.D.
saraiya@musce.edu
8438762374
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2027-08
Participants
Target number of participants: 76
Treatments
Experimental: HOPE Therapy
Helping Opioid Use and PTSD with Exposure (HOPE) therapy is an integrated 10-12 week treatment for opioid use disorder and trauma/posttraumatic stress disorder
No_intervention: Treatment as Usual
Participants take medications as prescribed and attend standard community substance use treatment services
Related Therapeutic Areas
Opioid Use Disorder
Post-Traumatic Stress Disorder (PTSD)
Sponsors
Collaborators: National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH)
Leads: Medical University of South Carolina

This content was sourced from clinicaltrials.gov

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