Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial Agents in Patients Patients With Neuromotor Disability : a Prospective Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

People with neuromotor disability (i.e. following an inborn or acquired spinal cord, cerebral or peripheral neurological lesion) are at high risk of osteomyelitis-associated pressure ulcers. The management of osteomyelitis-associated pressure ulcers is controversial. In our center, patients benefit from a one stage surgical management with bone shaving and flap covering osteitis of pressure ulcer to perform wound closing. Surgery is followed by an antibiotic treatment, secondarily adapted to intraoperative samples. The aim of this study is to describe the cohort and to identify factors associated with failure (or success) in this frail population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
View:

• Patients \>= 18 years old ;

• Treated in the Perioperative Disability Unit (UPOH) of the Physical Medicine and Rehabilitation Department of our university hospital;

• Admitted for the treatment of an osteomyelitis-associated pressure ulcer by surgical flap;

• Having a neuromotor disability;

• No opposition to be enrolled in the study from the patient, or from a legally authorized close relative if the patient's state of health does not allow it;

• Affiliation to a social security scheme.

Locations
Other Locations
France
Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, AP-HP
RECRUITING
Garches
Contact Information
Primary
François Genêt, MD-PhD
françois.genet@aphp.fr
+ 33 1 47 10 70 82
Backup
Vincent T. Carpentier, MD-MSc
vincent.carpentier@ispc-synergies.org
+ 33 1 47 10 70 82
Time Frame
Start Date: 2023-02-19
Estimated Completion Date: 2027-02-01
Participants
Target number of participants: 400
Treatments
Subjects with osteomyelitis-associated pressure ulcers
Subjects with neuromotor disability and admitted for the treatment of osteomyelitis-associated pressure ulcers
Related Therapeutic Areas
Sponsors
Leads: Institut de Sante Parasport Connecte Synergies
Collaborators: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov

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