Characterization of Epithelial Ovarian Cancer Patients in Terms of Homologous Recombination Phenotype - A Prospective Observational Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

This is a prospective observational multi-country, multi-center study of a large real-world cohort of first line (1L) epithelial ovarian cancer patients, exposed to standard of care (SOC) treatment stratified according to BRCA1/2 and HRD status.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 100
View:

• Patients with newly diagnosed histologically confirmed epithelial ovarian cancer:

‣ FIGO stage I-II with a known BRCA1/2 mutation (germline/gBRCA or somatic/tBRCA)

⁃ FIGO stage III-IV of any histology

• Women aged ≥18 years of age at the time of diagnosis

• Patients intended for platinum-based chemotherapy treatment

• Patients capable of giving signed informed consent, which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol

• Patients consent to provide archival tumor tissue sample

Locations
Other Locations
Denmark
Rigshospitalet
RECRUITING
København Ø
Contact Information
Primary
Mansoor R Mirza, MD
mansoor.raza.mirza@regionh.dk
004535459624
Backup
Henriette W Hansen, MSc
henriette.watson.hansen@regionh.dk
004535453372
Time Frame
Start Date: 2022-12-01
Estimated Completion Date: 2028-12-01
Participants
Target number of participants: 350
Treatments
Ovarian cancer patients
Newly diagnosed patients with ovarian cancer, fallopian tube cancer or primary peritoneal cancer
Related Therapeutic Areas
Sponsors
Leads: Nordic Society of Gynaecological Oncology - Clinical Trials Unit

This content was sourced from clinicaltrials.gov